CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFAD257
Family Name D(2) dopamine receptor Ligand Haloperidol Family
No. of Seeds 5 No. of Other Members 53
Family Centroid CFAMM00044684 Functional Category Approved Drug
Superfamily dopamine receptor ligand Haloperido,l opioid receptor ligand Loperamide Superfamily
Class Class 218

Cousin Family NamesSeedsMembers
Histamine H1 receptor Ligand Terfenadine Family 3 50
Delta-type opioid receptor Ligand Loperamide Family 8 55
Sodium channel protein type 5 subunit alpha Ligand Hexylcaine ... 4 94
Muscarinic acetylcholine receptor M1 Ligand Trihexyphenidyl Fa... 14 199
Noradrenergic re-uptake and Serotonin re-uptake Inhibitor Diet... 29 276
Histamine H1 receptor ligand diphenylpiperidine analog Dipheny... 13 224
Histamine H1 receptor Ligand Chlophedianol Family 4 46
Peptide deformylase, mitochondrial Inhibitor Hydroxamates Family 6 17
Cholinesterase Inhibitor 4-[4-(benzyloxy)piperidino]butyl-3-fl... 5 18
Glutamate receptor ionotropic, NMDA 2B and Glutamate receptor ... 9 7
Melanocortin receptor 4 and Melanocortin receptor 3 ligand Sur... 6 53
C-C chemokine receptor type 5 ligand N-[1-[[(3S,4R)-1-(cyclope... 1 16
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 3 13
3-oxo-5-alpha-steroid 4-dehydrogenase 2 and 3-oxo-5-alpha-ster... 2 7
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor SureC... 6 5
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor N-[4-... 30 10
Substance-K receptor ligand AGN-PC-0759BS family 3 6
Sigma non-opioid intracellular receptor 1 ligand methyl (1R,2S... 4 0
Melanin-concentrating hormone receptor 1 ligand 1-(3-acetyl-1,... 8 4
D(2) dopamine receptor and D(3) dopamine receptor ligand 4-(4-... 1 3
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 6 3
Malonyl-CoA decarboxylase, mitochondrial inhibitor [4-(1,1,1,3... 6 0
C-C chemokine receptor type 5 ligand (2R)-3-cyclopropyl-2-[(3S... 6 0
C-C chemokine receptor type 1 ligand 4-chloro-N-[(2R)-1-[(4S)-... 6 3
C-C chemokine receptor type 1 ligand N-[(2R)-1-[4-(4-chlorophe... 2 0
C-C chemokine receptor type 5 ligand AC1LAX0N family 2 0
Histamine H1 receptor and 5-hydroxytryptamine receptor 2C liga... 1 0
Delta-type opioid receptor and Kappa-type opioid receptor liga... 3 4


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00044684 DAP000313 Approved Drug Haloperidol
CFAMM00044729 CHEMBL478617 Bioactive AGN-PC-00KUJV
CFAMM00044681 CHEMBL553327 Bioactive AGN-PC-00KUJW
CFAMM00044725 CHEMBL1257689 Bioactive AGN-PC-087V2M
CFAMM00044708 DCL001008 Clinical Trial Drug SUN13834

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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