CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Glucocorticoid receptor ligand glucocorticoid analog Flunisolide Family
No. of Seeds 10 No. of Other Members 41
Family Centroid CFAMM00045071 Functional Category Approved Drug with Human Metabolite & Natural Product
Superfamily Glucocorticoid receptor, Corticosteroid-binding globulin, Phospholipase A2 binding glucocorticoid, corticosteroid, Propionate Superfamily
Class Class 7

Cousin Family NamesSeedsMembers
Glucocorticoid receptor ligand glucocorticoid analog Dexameth... 13 248
Corticosteroid-binding globulin inhibitor corticosteroid analo... 6 10
Corticosteroid-binding globulin Inhibitor Rimexolone Family 6 138
Corticosteroid-binding globulin inhibitor corticosteroid analo... 11 112
Androgen receptor ligand anabolic androgenic steroid Testoster... 8 198
Glucocorticoid receptor Ligand Fluticasone Propionate Family 3 5
Glucocorticoid receptor ligand corticosteroid Prednisone Family 2 1
Phospholipase A2 Inhibitor Halobetasol Propionate Family 3 5
Phospholipase A2 Inhibitor Hydrocortamate Family 1 0
Asiaticoside family 7 39
Convallatoxin family 2 11
Glucocorticoid receptor ligand CHEMBL158091 family 3 0
Glucocorticoid receptor and Interstitial collagenase ligand Su... 12 11
Integrin alpha-L inhibitor Cucurbitacin E family 1 0
Steroids and Steroid Derivatives Metabolite 14alpha-Hydroxyixo... 1 4


External ID

Functional Category

Molecule Name

CFAMM00045079 DAP000423 Approved Drug Ciclesonide
CFAMM00045071 DAP001046 Approved Drug Flunisolide
CFAMM00045095 DAP001188 Approved Drug Desonide
CFAMM00045078 DAP000421 Approved Drug Fluocinonide
CFAMM00045070 DAP001044 Approved Drug Amcinonide
CFAMM00045156 DAP000320 Approved Drug Budesonide
CFAMM00045148 DAP000418 Approved Drug Flurandrenolide
CFAMM00045088 DAP000813 Approved Drug Fluocinolone Acetonide
CFAMM00045131 CHEMBL1370 Bioactive budesonide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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