CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFAD265
Family Name Histamine H1 receptor Ligand Clemastine Family
No. of Seeds 5 No. of Other Members 76
Family Centroid CFAMM00045252 Functional Category Approved Drug
Superfamily Histamine H1 receptor Ligand Clemastine Superfamily
Class Class 225

Cousin Family NamesSeedsMembers
Opioid receptor ligand synthetic opioid methadone analog Dextr... 2 108
Histamine H1 receptor Ligand Diphenhydramine Family 5 75
Alpha-1B adrenergic receptor ligand Morpholine derivative Phen... 4 152
Histamine H1 receptor ligand diphenylpiperidine analog Dipheny... 13 224
Histamine H1 receptor Ligand Chlophedianol Family 4 46
Nicotinic acetylcholine receptor Ligand Benztropine Mesylate F... 10 20
5-hydroxytryptamine receptor 2A and D(2) dopamine receptor Lig... 4 35
Pitolisant family 4 24
Peptide deformylase, mitochondrial Inhibitor Hydroxamates Family 6 17
Histamine H3 receptor Ligand A-331440 Family 6 7
Substance-P receptor Ligand L-733060 Family 19 71
Adenosine receptor A3 and Mu-type opioid receptor Ligand GBR-1... 80 110
Substance-P receptor Ligand SCH-388714 Family 26 8
Potassium voltage-gated channel subfamily A member 5 Ligand 2-... 3 1
Potassium voltage-gated channel subfamily H member 2 and Sodiu... 5 14
Glutamate receptor ionotropic, NMDA 2B and Glutamate receptor ... 9 7
Sodium-dependent dopamine transporter and Sodium-dependent ser... 3 18
D(4) dopamine receptor and D(2) dopamine receptor ligand 4-(4-... 2 6
Muscarinic acetylcholine receptor M3 ligand 3-[8-methyl-8-(2-p... 3 0
Substance-P receptor ligand (1R,2S,3S)-3-[(1R)-1-[3,5-bis(trif... 8 0
Sodium-dependent serotonin transporter and Substance-P recepto... 2 2
Sodium-dependent serotonin transporter and Sodium-dependent do... 9 1
Sodium-dependent dopamine transporter and Sodium-dependent ser... 3 0
Sodium-dependent dopamine transporter and Sodium-dependent ser... 3 3
Substance-P receptor ligand AGN-PC-02K8GG family 1 1
Sodium-dependent dopamine transporter and Sigma non-opioid int... 2 0
Cannabinoid receptor 2 ligand SureCN4472215 family 2 0
Sodium-dependent dopamine transporter and Sodium-dependent ser... 2 5


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00045252 DAP000322 Approved Drug Clemastine
CFAMM00045228 CHEMBL566845 Bioactive AGN-PC-07CRPQ
CFAMM00045182 CHEMBL578369 Bioactive 3-[(4-chlorophenyl)methoxy]-3-phenyl-8-azabicyclo[3.2.1]octane
CFAMM00045218 DNC000753 Investigative Drug Hydroxyclemastine
CFAMM00045224 DNC013136 Investigative Drug 3alpha-(bis-chloro-phenylmethoxy)tropane

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

21768 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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