CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFAD280
Family Name Muscarinic acetylcholine receptor Ligand Flutropium Bromide Family
No. of Seeds 6 No. of Other Members 45
Family Centroid CFAMM00046123 Functional Category Approved Drug with Human Metabolite & Natural Product
Superfamily Muscarinic acetylcholine receptor Ligand Flutropium Bromide Superfamily
Class Class 237

Cousin Family NamesSeedsMembers
Sodium-dependent dopamine transporter inhibitor substituted ph... 22 416
Histamine H1 receptor Ligand Terfenadine Family 3 50
Alpha-2 adrenergic receptor ligand opiate Meperidine Family 13 76
Muscarinic acetylcholine receptor M2 ligand Tropane alkaloid S... 7 16
Muscarinic acetylcholine receptor M5 ligand Tropane alkaloid A... 18 12
Sodium channel protein type 5 subunit alpha Ligand Hexylcaine ... 4 94
Dopamine reuptake and Noradrenergic re-uptake Inhibitor Cocain... 13 136
Muscarinic acetylcholine receptor Ligand Oxyphencyclimine Family 1 2
Histamine H1 receptor ligand diphenylpiperidine analog Dipheny... 13 224
Muscarinic acetylcholine receptor Ligand Cyclopentolate Family 10 11
Muscarinic acetylcholine receptor Ligand Mepenzolate Family 35 11
Muscarinic acetylcholine receptor M1 Ligand Oxyphenonium Family 12 5
Sodium-dependent dopamine transporter Inhibitor Ioflupane I-12... 130 181
Sodium-dependent noradrenaline transporter Inhibitor (r)-1-((s... 3 8
Cholinesterase Inhibitor 4-[4-(benzyloxy)piperidino]butyl-3-fl... 5 18
Muscarinic acetylcholine receptor M1 and Muscarinic acetylchol... 4 1
Sigma non-opioid intracellular receptor 1 ligand SureCN5315520... 3 11
Sigma non-opioid intracellular receptor 1 ligand methyl (1R,2S... 4 0
Muscarinic acetylcholine receptor M3 ligand (1,1-dimethylpiper... 7 1
Muscarinic acetylcholine receptor M1 and Muscarinic acetylchol... 2 0
Acetylcholine-binding protein and Soluble acetylcholine recept... 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00046124 DAP000342 Approved Drug Trospium
CFAMM00046123 DNAP001493 Approved Drug Flutropium bromide
CFAMM00046156 DAP000823 Approved Drug Homatropine Methylbromide
CFAMM00046140 CHEMBL140277 Bioactive [1-(1-fluoropropan-2-yl)piperidin-4-yl] 2-hydroxy-2,2-diphenylacetate
CFAMM00046113 CHEMBL341731 Bioactive AGN-PC-075OKG
CFAMM00046157 CHEMBL140993 Bioactive (1-propan-2-ylpiperidin-4-yl) 2-hydroxy-2,2-diphenylacetate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

21767 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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