CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Muscarinic acetylcholine receptor M2 ligand Tropane alkaloid Scopolamine Family
No. of Seeds 7 No. of Other Members 16
Family Centroid CFAMM00046208 Functional Category Approved Drug with Human Metabolite & Natural Product
Superfamily Muscarinic acetylcholine receptor ligand Tropane alkaloid Atropine Scopolamine Superfamily
Class Class 238

Cousin Family NamesSeedsMembers
Sodium-dependent dopamine transporter inhibitor substituted ph... 22 416
Alpha-2 adrenergic receptor ligand opiate Meperidine Family 13 76
Muscarinic acetylcholine receptor Ligand Flutropium Bromide Fa... 6 45
Muscarinic acetylcholine receptor M5 ligand Tropane alkaloid A... 18 12
Muscarinic acetylcholine receptor Ligand Mepenzolate Family 35 11
Muscarinic acetylcholine receptor M1 Ligand Oxyphenonium Family 12 5
Sodium-dependent dopamine transporter Inhibitor Ioflupane I-12... 130 181
Sodium-dependent noradrenaline transporter Inhibitor (r)-1-((s... 3 8
Muscarinic acetylcholine receptor M3 ligand (1,1-dimethylpiper... 7 1


External ID

Functional Category

Molecule Name

CFAMM00046190 DAP001126 Approved Drug Methylscopolamine
CFAMM00046185 DNAP001573 Approved Drug Oxitropium bromide
CFAMM00046199 DNAP001548 Approved Drug Cimetropium bromide
CFAMM00046208 DAP000343 Approved Drug Scopolamine
CFAMM00046198 DNAP001612 Approved Drug Anisodine
CFAMM00046188 DNC000757 Investigative Drug Hyoscine
CFAMM00046181 DNC000152 Investigative Drug Act1

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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