CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFAD284
Family Name Muscarinic acetylcholine receptor M5 Ligand Metixene Family
No. of Seeds 5 No. of Other Members 24
Family Centroid CFAMM00046337 Functional Category Approved Drug
Superfamily Muscarinic acetylcholine receptor M5 Ligand Metixene Superfamily
Class Class 241

Cousin Family NamesSeedsMembers
Muscarinic acetylcholine receptor M3 Ligand Diphemanil Methyls... 22 45
Glutamate receptor ionotropic, NMDA 2A and Glutamate receptor ... 2 39
5-hydroxytryptamine receptor 5A and 5-hydroxytryptamine recept... 12 20
Potassium voltage-gated channel subfamily H member 2 Ligand 4-... 4 26
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 15 11
Sodium-dependent dopamine transporter Inhibitor 1-(1-benzo[b]t... 5 5
D(2) dopamine receptor Ligand 4-[3-(methylsulfonyl)phenyl]-1-p... 2 2
5-hydroxytryptamine receptor 1A Ligand 2-(biphenyl-3-ylthio)-n... 1 3
Sodium-dependent serotonin transporter Inhibitor 2-n-ethylamin... 14 5
5-hydroxytryptamine receptor 6 ligand (1R)-1-[(dimethylsulfamo... 10 4
5-hydroxytryptamine receptor 1A ligand (2R)-N,N-dipropyl-8-thi... 2 4
5-hydroxytryptamine receptor 2A and Potassium voltage-gated ch... 2 11
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 2 0
Sigma non-opioid intracellular receptor 1 and 3-beta-hydroxyst... 4 12
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 3 10
Muscarinic acetylcholine receptor M2 and Muscarinic acetylchol... 2 2
Squalene synthase inhibitor SureCN8712667 family 1 0
Sodium-dependent serotonin transporter and Sodium-dependent no... 1 1
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 3 1
5-hydroxytryptamine receptor 2A and Muscarinic acetylcholine r... 1 2
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 4 5
D(4) dopamine receptor and 5-hydroxytryptamine receptor 2A lig... 1 1
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00046337 DAP000346 Approved Drug Metixene
CFAMM00046326 CHEMBL152408 Bioactive pimethixene
CFAMM00046306 CHEMBL305218 Bioactive AGN-PC-074GLM
CFAMM00046308 DNCL003788 Clinical Trial Drug Lu AA24530
CFAMM00046310 DNCL003059 Clinical Trial Drug Tedatioxetine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

21767 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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