CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Prostaglandin E2 receptor EP2 subtype Ligand Alprostadil Family
No. of Seeds 11 No. of Other Members 127
Family Centroid CFAMM00046706 Functional Category Approved Drug with Human Metabolite & Natural Product
Superfamily Prostaglandin E2 receptor EP2 subtype Ligand Alprostadil Superfamily
Class Class 199

Cousin Family NamesSeedsMembers
Prostaglandin E2 receptor EP2 subtype Ligand Iloprost Family 2 37
Prostacyclin receptor Ligand Dinoprost Tromethamine Family 2 1
Prostacyclin receptor Ligand Epoprostenol Family 4 33
Unoprostone Isopropyl Ester family 1 3
Prostaglandin G/H synthase 2 Inhibitor Prostaglandin G2 Family 2 0
Prelamin-A/C and Nonstructural protein 1 inhibitor prostagland... 1 7
Prostaglandin E2 receptor EP4 subtype and Prostaglandin E2 rec... 5 6
Prostaglandin E2 receptor EP2 subtype and Prostaglandin E2 rec... 1 3
Eicosanoids Metabolite 15-Keto-13,14-dihydroprostaglandin A2 F... 1 11
3,11-dihydroxy-2,4,6,8,10,12-hexamethyl-9-oxotetradec-6-enoate... 8 4


External ID

Functional Category

Molecule Name

CFAMM00046705 DAP000358 Approved Drug Misoprostol
CFAMM00046668 DNAP001487 Approved Drug Limaprost
CFAMM00046730 DAP000360 Approved Drug Dinoprostone
CFAMM00046688 DNAP001574 Approved Drug Gemeprost
CFAMM00046736 DNAP001513 Approved Drug Ornoprostil
CFAMM00046706 DAP000359 Approved Drug Alprostadil
CFAMM00046749 CHEMBL1628651 Bioactive [3H]PGE2
CFAMM00046816 CHEMBL64804 Bioactive 15-epi-Dinoprostone
CFAMM00046802 CHEMBL360785 Bioactive AC1O75CE
CFAMM00046759 CHEMBL180344 Bioactive SureCN4083910
CFAMM00046769 DNC008058 Investigative Drug BUTAPROST

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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