CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name 5-hydroxytryptamine receptor 1A ligand azapirone derivative Buspirone Family
No. of Seeds 4 No. of Other Members 20
Family Centroid CFAMM00007321 Functional Category Approved Drug with Human Metabolite
Superfamily 5HT receptor binding azapirones Superfamily
Class Class 29

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor ligand azapirone derivative Tando... 7 16
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 5 7


External ID

Functional Category

Molecule Name

CFAMM00007321 DAP000031 Approved Drug Buspirone
CFAMM00007323 CHEMBL297099 Bioactive AGN-PC-073PY4
CFAMM00007310 DCL000413 Clinical Trial Drug GSK2190915
CFAMM00007327 DCL000813 Clinical Trial Drug Gepirone ER

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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