CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name D(2) dopamine receptor ligand Benzisoxazole Derivative Risperidone family
No. of Seeds 3 No. of Other Members 32
Family Centroid CFAMM00000331 Functional Category Approved Drug with Natural Product
Superfamily D(2) dopamine receptor ligand Benzisoxazole Derivative Risperidone Superfamily
Class Class 3

Cousin Family NamesSeedsMembers
Prostaglandin G/H synthase 2 Inhibitor Benzisoxazole Derivativ... 8 38
Cystic fibrosis transmembrane conductance regulator and Anocta... 12 74
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 6 159
Sodium-dependent dopamine transporter Inhibitor RTI-336 Family 21 61
Acetylcholinesterase and Cholinesterase inhibitor Icopezil mal... 10 14
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 4 10
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 2 15
D(4) dopamine receptor ligand AGN-PC-087ZJG family 3 13
Nuclear receptor subfamily 4 group A member 2 ligand 6-[4-(2-m... 2 33
5-hydroxytryptamine receptor 7 and 5-hydroxytryptamine recepto... 4 1
Acetylcholinesterase inhibitor SureCN6987022 family 4 11
5-hydroxytryptamine receptor 2A and D(2) dopamine receptor lig... 3 0
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 1 0


External ID

Functional Category

Molecule Name

CFAMM00000331 DAP000003 Approved Drug Risperidone
CFAMM00000343 DAP000847 Approved Drug Paliperidone
CFAMM00000315 DCL000803 Clinical Trial Drug FG-3019

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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