CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Corticosteroid-binding globulin inhibitor corticosteroid analog Beclomethasone Family
No. of Seeds 6 No. of Other Members 10
Family Centroid CFAMM00048997 Functional Category Approved Drug with Natural Product
Superfamily Glucocorticoid receptor, Corticosteroid-binding globulin, Phospholipase A2 binding glucocorticoid, corticosteroid, Propionate Superfamily
Class Class 7

Cousin Family NamesSeedsMembers
Glucocorticoid receptor ligand glucocorticoid analog Dexameth... 13 248
Glucocorticoid receptor ligand glucocorticoid analog Flunisol... 10 41
Corticosteroid-binding globulin Inhibitor Rimexolone Family 6 138
Corticosteroid-binding globulin inhibitor corticosteroid analo... 11 112
Androgen receptor ligand anabolic androgenic steroid Testoster... 8 198
Progesterone receptor ligand steroidal progestin Medroxyproges... 6 20
Glucocorticoid receptor Ligand Fluticasone Propionate Family 3 5
Glucocorticoid receptor ligand corticosteroid Prednisone Family 2 1
Phospholipase A2 Inhibitor Halobetasol Propionate Family 3 5
Phospholipase A2 Inhibitor Hydrocortamate Family 1 0
Trimegestone family 7 25
Ecdysone receptor ligand Ponasterone A family 1 22
Integrin alpha-L inhibitor Cucurbitacin E family 1 0


External ID

Functional Category

Molecule Name

CFAMM00048981 DAP001042 Approved Drug Mometasone
CFAMM00048997 DAP000416 Approved Drug Beclomethasone
CFAMM00048996 DAP000415 Approved Drug Alclometasone
CFAMM00048985 DAP001183 Approved Drug Clobetasol
CFAMM00048984 DNAP001572 Approved Drug Halometasone
CFAMM00048983 DAP001190 Approved Drug Clocortolone

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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