CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFAD313
Family Name Corticosteroid-binding globulin Inhibitor Rimexolone Family
No. of Seeds 6 No. of Other Members 138
Family Centroid CFAMM00049171 Functional Category Approved Drug with Human Metabolite & Natural Product
Superfamily Corticosteroid-binding globulin Inhibitor Rimexolone Superfamily
Class Class 254

Cousin Family NamesSeedsMembers
Glucocorticoid receptor ligand glucocorticoid analog Dexameth... 13 248
Vitamin D3 receptor ligand Vitamin D analog Cholecalciferol Fa... 7 270
Glucocorticoid receptor ligand glucocorticoid analog Flunisol... 10 41
Corticosteroid-binding globulin inhibitor corticosteroid analo... 6 10
Steroid 17-alpha-hydroxylase/17,20 lyase Inhibitor Progesteron... 20 283
Corticosteroid-binding globulin inhibitor corticosteroid analo... 11 112
Androgen receptor ligand Anabolic steroid Dromostanolone Family 9 408
Androgen receptor ligand anabolic androgenic steroid Testoster... 8 198
Progesterone receptor ligand steroidal progestin Etonogestrel ... 8 31
Progesterone receptor ligand steroidal progestin Medroxyproges... 6 20
Elongation factor G Inhibitor Fusidic Acid Family 3 34
Glucocorticoid receptor Ligand Fluticasone Propionate Family 3 5
Glucocorticoid receptor ligand corticosteroid Prednisone Family 2 1
Phospholipase A2 Inhibitor Halobetasol Propionate Family 3 5
Mineralocorticoid receptor ligand steroid progestogen analog D... 3 240
Phospholipase A2 Inhibitor Hydrocortamate Family 1 0
Dienogest family 1 3
Hydroxyprogesterone family 4 37
Trimegestone family 7 25
Oestrogen receptor Ligand Gestrinone Family 2 2
HE3286 family 5 34
Aminopeptidase N Inhibitor [(125)i] RB129 Family 11 204
Nuclear receptor subfamily 1 group I member 2 Ligand Pregnenol... 1 1
Lanosterol synthase Inhibitor Lanosterol Family 2 62
Tyrosine-protein phosphatase non-receptor type 1 Ligand Uvaol ... 3 24
Farnesyltransferase beta subunit, putative and Protein farnesy... 1 2
Glycogen phosphorylase, muscle form and Tyrosine-protein phosp... 4 12
DNA polymerase and Glycogen phosphorylase, muscle form Inhibit... 32 22
Prostaglandin G/H synthase 2 Inhibitor 8alpha,19-dihydroxylabd... 2 10
Aldose reductase Inhibitor Tingenin B Family 2 0
Aromatase inhibitor (10R,13S)-13-methyl-10-(oxiran-2-yl)-2,6,7... 1 0
Aromatase inhibitor [(6R)-10,13-dimethyl-17-oxo-1,2,3,6,7,8,9,... 4 17
Glucocorticoid receptor and Interstitial collagenase ligand Su... 12 11
Ecdysone receptor ligand Ponasterone A family 1 22
Bile acid receptor and Prolyl endopeptidase ligand beta-Elemon... 1 4
Potassium-transporting ATPase alpha chain 2 and Sodium/potassi... 1 0
Carbonic anhydrase 2 and Carbonic anhydrase 1 inhibitor [(10R,... 3 0
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor CALON... 2 24
Steroid 17-alpha-hydroxylase/17,20 lyase inhibitor CHEMBL21127... 1 7
Integrin alpha-L inhibitor Cucurbitacin E family 1 0
Glucocorticoid receptor ligand (9R,10S,11S,13S,16R,17R)-9-fluo... 1 6
Prostaglandin G/H synthase 2 inhibitor bruguierins A family 1 4
Prenol Lipids Metabolite 4a-Carboxy-4b-methyl-5a-cholesta-8,24... 4 0
Prenol Lipids Metabolite Yucalexin B14 Family 1 2
Prenol Lipids Metabolite (ent-7alpha)-7-Hydroxy-8(14),15-pimar... 2 22
Prenol Lipids Metabolite Ineketone Family 1 0
Putative NP ZINC04029475 Family 4 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00049071 DAP001344 Approved Drug Aldosterone
CFAMM00049171 DAP000420 Approved Drug Rimexolone
CFAMM00049069 DAP001048 Approved Drug Medrysone
CFAMM00049185 DAP001185 Approved Drug Desoximetasone
CFAMM00049155 DNCL002110 Clinical Trial Drug AC430
CFAMM00049216 DNC002614 Investigative Drug (11-BETA)-11,21-DIHYDROXY-PREGN-4-ENE-3,20-DIONE

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

21767 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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