CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Calmodulin inhibitor phenothiazine derivative Trifluoperazine Family
No. of Seeds 3 No. of Other Members 30
Family Centroid CFAMM00007415 Functional Category Approved Drug
Superfamily Biogenic amine receptor, Calmodulin binding phenothiazine Superfamily
Class Class 32

Cousin Family NamesSeedsMembers
Alpha adrenergic receptor ligand phenothiazine derivative Thio... 4 10
Muscarinic acetylcholine receptor M5 ligand phenothiazine deri... 8 37
Alpha-1B adrenergic receptor Ligand Propericiazine Family 2 0
Histamine H1 receptor ligand phenothiazine derivative Mequitaz... 3 2
5-hydroxytryptamine receptor Ligand Lu AA21004 Family 13 39
5-hydroxytryptamine receptor 6 Ligand 4-(4-benzenesulfonamidop... 4 5
5-hydroxytryptamine receptor 2A Ligand Cinanserin Family 3 27
Sodium-dependent serotonin transporter and Sodium-dependent no... 6 1
Sodium-dependent serotonin transporter and Transporter inhibit... 4 0


External ID

Functional Category

Molecule Name

CFAMM00007386 DAP000375 Approved Drug Fluphenazine
CFAMM00007415 DAP000034 Approved Drug Trifluoperazine
CFAMM00007392 DAP000294 Approved Drug Triflupromazine

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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