CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Penicillin binding protein inhibitor β-lactam cephalosporin Cephalexin Family
No. of Seeds 3 No. of Other Members 38
Family Centroid CFAMM00051372 Functional Category Approved Drug with Natural Product
Superfamily Penicillin binding protein inhibitor β-lactam carbacephem cephalosporin Cephalexin Superfamily
Class Class 260

Cousin Family NamesSeedsMembers
Penicillin binding protein inhibitor β-lactam aminopenicillin ... 12 359
Penicillin binding protein inhibitor β-lactam carbacephem Lora... 1 5
Penicillin binding protein Inhibitor Cefadroxil Family 5 17
Angiotensin-converting enzyme Inhibitor Spirapril Family 17 86
Penicillin binding protein inhibitor β-lactam aminopenicillin ... 3 1
Penicillin binding protein inhibitor β-lactam ureidopenicillin... 4 9
Neuromedin-K receptor Ligand Senktide Family 15 22
Caspase-3 and Caspase-7 inhibitor valine aspartyl ketone 16 fa... 3 0
Capsid scaffolding protein inhibitor 2-[(2S)-2-[[(2S)-2-(3,3-d... 1 3
Neutrophil elastase inhibitor (2S)-2-[[(7S)-7-methoxy-2-[(2-me... 1 0


External ID

Functional Category

Molecule Name

CFAMM00051372 DAP000437 Approved Drug Cephalexin
CFAMM00051394 DAP000442 Approved Drug Cefaclor
CFAMM00051400 DAP001158 Approved Drug Cephaloglycin

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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