CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Solute carrier family 12 member 1 inhibitor hydrochlorothiazide analog Methyclothiazide family
No. of Seeds 4 No. of Other Members 4
Family Centroid CFAMM00007425 Functional Category Approved Drug
Superfamily Carbonic anhydrase, Solute carrier binding Cyclothiazide Superfamily
Class Class 33

Cousin Family NamesSeedsMembers
Carbonic anhydrase 2 Inhibitor Cyclothiazide Family 1 0
Carbonic anhydrase 2 Inhibitor Chlorothiazide Family 1 1
Carbonic anhydrase 2 and Carbonic anhydrase 4 inhibitor N-(5-c... 4 18


External ID

Functional Category

Molecule Name

CFAMM00007428 DAP000751 Approved Drug Polythiazide
CFAMM00007427 DAP000750 Approved Drug Hydrochlorothiazide
CFAMM00007425 DAP000746 Approved Drug Methyclothiazide
CFAMM00007433 DAP000035 Approved Drug Trichlormethiazide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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