CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFAD346
Family Name Alpha adrenergic receptor Ligand Tolazoline Family
No. of Seeds 7 No. of Other Members 51
Family Centroid CFAMM00052046 Functional Category Approved Drug
Superfamily Alpha adrenergic receptor Ligand Tolazoline Superfamily
Class Class 45

Cousin Family NamesSeedsMembers
Beta adrenergic receptor Ligand Bethanidine Family 2 22
Alpha-1B adrenergic receptor ligand phenethylamine derivative ... 12 283
AMP-activated protein kinase Inhibitor Phenformin Family 5 14
Alpha-2A adrenergic receptor Ligand Brl 44408 Family 1 0
Alpha-2A adrenergic receptor and Alpha-2B adrenergic receptor ... 1 1
5-hydroxytryptamine receptor 1D and Alpha-1A adrenergic recept... 3 22
Nitric oxide synthase, brain Inhibitor 1-(benzhydrylamino)etha... 1 4
Nitric oxide synthase, inducible and Nuclear factor NF-kappa-B... 1 2
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 4 6
Alpha-2A adrenergic receptor and Alpha-2B adrenergic receptor ... 1 1
Dihydrofolate reductase inhibitor 5-[(3,5-dimethylphenyl)methy... 4 9
Sigma non-opioid intracellular receptor 1 and 5-hydroxytryptam... 1 0
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 1 0
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 1 1
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 1 2
Potassium voltage-gated channel subfamily H member 2 ligand Su... 1 0
5-hydroxytryptamine receptor 3E and 5-hydroxytryptamine recept... 1 2
Sodium channel protein type 1 subunit alpha and Sodium channel... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00052063 DAP001408 Approved Drug Naphazoline
CFAMM00052046 DAP000477 Approved Drug Tolazoline
CFAMM00052038 CHEMBL1706 Bioactive NAPHAZOLINE HYDROCHLORIDE
CFAMM00052082 CHEMBL1200413 Bioactive Tetrahydrozoline hydrochloride
CFAMM00052068 DNC012787 Investigative Drug 2-Naphthalen-2-ylmethyl-4,5-dihydro-1H-imidazole
CFAMM00052060 DNC012450 Investigative Drug 2-Phenethyl-4,5-dihydro-1H-imidazole
CFAMM00052034 DNC005056 Investigative Drug 2-(2,6-Dimethyl-benzyl)-4,5-dihydro-1H-imidazole

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

21794 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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