CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFAD348
Family Name Beta adrenergic receptor Ligand Metipranolol Family
No. of Seeds 5 No. of Other Members 1
Family Centroid CFAMM00052174 Functional Category Approved Drug
Superfamily Adrenergic receptor ligand Propranolol Levobunolol Metipranolol Superfamily
Class Class 80

Cousin Family NamesSeedsMembers
Beta adrenergic receptor ligand naphthol derivative Propranolo... 11 218
Serotonin re-uptake Inhibitor Fluoxetine Family 18 682
Alpha-1 adrenergic receptor ligand Dextroamphetamine derivativ... 5 29
Beta adrenergic receptor Ligand Levobunolol Family 6 133
Beta-1 adrenergic receptor Ligand Esmolol Family 5 39
Beta-1 adrenergic receptor Ligand Metoprolol Family 29 90
Beta-1 adrenergic receptor Ligand Oxprenolol Family 3 27
Beta adrenergic receptor Ligand Dipivefrin Family 3 55
Noradrenergic re-uptake Inhibitor Reboxetine Family 26 206
Alpha adrenergic receptor Ligand Bevantolol Family 4 48
Beta-1 adrenergic receptor Ligand Nebivolol Family 5 22
5-hydroxytryptamine receptor 2A Ligand Sarpogrelate Family 2 15
5-hydroxytryptamine receptor 2A and Sodium-dependent serotonin... 2 5
Potassium voltage-gated channel subfamily H member 2 Ligand Al... 2 3
M-phase inducer phosphatase 1 Inhibitor Naphthoquinone Analogs... 11 56
Extracellular calcium-sensing receptor and Potassium voltage-g... 3 11
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 5 11
Sodium-dependent dopamine transporter and Sodium-dependent nor... 6 2
5-hydroxytryptamine receptor 2A Ligand C-(9h-xanthen-9-yl)-met... 3 5
Sphingosine 1-phosphate receptor 1 and Sphingosine 1-phosphate... 1 0
Muscarinic acetylcholine receptor M2 and Muscarinic acetylchol... 7 1
Sodium-dependent noradrenaline transporter and Sodium-dependen... 1 5
Sodium-dependent noradrenaline transporter and Cytochrome P450... 11 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00052174 DAP000480 Approved Drug Metipranolol
CFAMM00052178 CHEMBL1256784 Bioactive ICI 118,551 hydrochloride
CFAMM00052180 DNC000769 Investigative Drug ICI 118,551
CFAMM00052177 DNC000770 Investigative Drug ICI 118.551

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

21783 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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