CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFAD349
Family Name Beta-1 adrenergic receptor Ligand Acebutolol Family
No. of Seeds 2 No. of Other Members 27
Family Centroid CFAMM00052186 Functional Category Approved Drug with Natural Product
Superfamily Beta-1 adrenergic receptor Ligand Acebutolol Superfamily
Class Class 281

Cousin Family NamesSeedsMembers
Beta-1 adrenergic receptor Ligand Practolol Family 2 82
D(4) dopamine receptor Ligand PD-165167 Family 2 96
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Cilost... 6 202
Amine oxidase [flavin-containing] A Inhibitor Ethyl 4-(2-oxo-2... 4 117
Leukotriene A-4 hydrolase Inhibitor N5-[4-(phenylmethoxy)pheny... 7 49
Leukotriene A-4 hydrolase Inhibitor N-benzyl-4-[(2r)-pyrrolidi... 6 40
Beta-1 adrenergic receptor and Beta-2 adrenergic receptor Liga... 40 90
Cytochrome P450 1B1 Inhibitor N-(2,4-dimethoxy-phenyl)-3,5-dim... 1 110
Substance-K receptor Ligand MEN-14933 Family 13 154
Alpha-1A adrenergic receptor Ligand Upidosin Family 8 46
Cannabinoid receptor 1 Ligand N-(4-methoxyphenyl)oleamide Family 4 23
Amyloid beta A4 protein Inhibitor 6-iodo-4'-methylaminoflavone... 3 33
Proto-oncogene tyrosine-protein kinase receptor Ret Ligand (z)... 1 60
Reverse transcriptase Inhibitor 10-propyl-10h-dibenzo[b,f][1,4... 9 60
Metabotropic glutamate receptor 5 Ligand N-(3-(3-cyanobenzamid... 2 13
Gamma-aminobutyric acid receptor Ligand 2-(2-amino-phenyl)-6-m... 4 23
Beta-1 adrenergic receptor ligand 1-[2-[[(2S)-3-(2-cyanophenox... 10 4
Beta-2 adrenergic receptor and Beta-1 adrenergic receptor liga... 3 6
Beta-1 adrenergic receptor ligand 4-[2-[[(2S)-3-(2-cyano-5-flu... 3 2
Histamine H3 receptor and Potassium voltage-gated channel subf... 3 4
Integrin beta-3 and Integrin alpha-IIb inhibitor AGN-PC-02INEQ... 6 6
Multidrug resistance protein 1 inhibitor 1-[2-[(2R)-3-[4-(2,3-... 2 41
Nuclear receptor ROR-gamma and Menin ligand CHEMBL1432265 family 1 18
Beta-3 adrenergic receptor and Beta-1 adrenergic receptor liga... 6 1
Neuronal acetylcholine receptor subunit alpha-7 and Potassium ... 1 2
Sphingosine 1-phosphate receptor 1 ligand 2-methoxy-N-[(4-phen... 2 23
Bifunctional epoxide hydrolase 2 inhibitor 3-[4-[[4-(trifluoro... 5 22
C-C chemokine receptor type 1 ligand N-[2-[(2S)-3-(5-chlorospi... 4 0
Bifunctional epoxide hydrolase 2 inhibitor 8-(2,6-difluorobenz... 4 1
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 1 5
Acyl-CoA desaturase 1 inhibitor AGN-PC-077KJY family 5 4
Acyl-CoA desaturase 1 inhibitor AGN-PC-077KFD family 1 1
Beta-1 adrenergic receptor and Beta-3 adrenergic receptor liga... 2 0
Amine oxidase [flavin-containing] B and Adenosine receptor A2b... 2 2
Glucose-dependent insulinotropic receptor ligand tert-butyl 4-... 1 0
Major prion protein and Microtubule-associated protein tau inh... 2 10
Sodium channel protein type 1 subunit alpha and Sodium channel... 3 0
Nuclear receptor ROR-gamma and Lethal factor ligand NSC211094 ... 1 3
cGMP-inhibited 3',5'-cyclic phosphodiesterase B and cGMP-inhib... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00052186 DAP000484 Approved Drug Acebutolol
CFAMM00052201 DNAP001569 Approved Drug Celiprolol hcl

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

21785 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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