CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFAD35
Family Name G protein-activated inward rectifier potassium channel 4 ligand sulfonylurea derivative Glibenclamide family
No. of Seeds 6 No. of Other Members 9
Family Centroid CFAMM00007513 Functional Category Approved Drug with Natural Product
Superfamily G protein-activated inward rectifier potassium channel 4 ligand sulfonylurea derivative Glibenclamide Superfamily
Class Class 35

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor Ligand Bay X3702 Family 3 12
Potassium voltage-gated channel subfamily A member 3 Ligand 2-... 9 92
Matrix metalloproteinase-9 and Collagenase 3 inhibitor AGN-PC-... 7 12
Pol polyprotein inhibitor AC1LA9K7 family 7 23
Carbonic anhydrase 9 and Carbonic anhydrase 14 inhibitor N-[2-... 6 10
Carbonic anhydrase 2 and Carbonic anhydrase 9 inhibitor zinc;4... 4 0
Sodium-dependent serotonin transporter and Potassium voltage-g... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00007513 DAP000037 Approved Drug Glibenclamide
CFAMM00007508 CHEMBL185671 Bioactive AGN-PC-075GJA
CFAMM00007515 CHEMBL500454 Bioactive 5-chloro-2-methoxy-N-(5-sulfamoyl-2,3-dihydro-1H-inden-2-yl)benzamide
CFAMM00007494 DNC004362 Investigative Drug HBR-985
CFAMM00007499 DNC000737 Investigative Drug HMR1883
CFAMM00007498 DNC000736 Investigative Drug HMR1098

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

21767 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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