CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFAD351
Family Name Calcium channel ligand dihydropyridine derivative Nicardipine Family
No. of Seeds 10 No. of Other Members 16
Family Centroid CFAMM00052278 Functional Category Approved Drug
Superfamily Calcium channel ligand dihydropyridine derivative Nisoldipine Nicardipine Superfamily
Class Class 212

Cousin Family NamesSeedsMembers
Calcium channel ligand dihydropyridine derivative Nisoldipine ... 18 94
Alpha-2A adrenergic receptor and Alpha-2B adrenergic receptor ... 19 32
Voltage-dependent L-type calcium channel subunit alpha-1F and ... 4 17
Voltage-dependent L-type calcium channel subunit alpha-1C and ... 1 0
Voltage-dependent L-type calcium channel subunit alpha-1C and ... 1 10
Voltage-dependent L-type calcium channel subunit alpha-1F and ... 7 1
Voltage-dependent L-type calcium channel subunit alpha-1C and ... 3 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00052263 DAP001261 Approved Drug Lercanidipine
CFAMM00052278 DAP000486 Approved Drug Nicardipine
CFAMM00052268 CHEMBL2303676 Bioactive S(+)-Niguldipine hydrochloride
CFAMM00052260 DNC010891 Investigative Drug MANIDIPINE
CFAMM00052270 DNC003951 Investigative Drug NIGULDIPINE
CFAMM00052284 DNC011785 Investigative Drug CGS-27830
CFAMM00052283 DNC011942 Investigative Drug CV-4093

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

21767 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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