CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFAD358
Family Name Potassium voltage-gated channel subfamily H member 2 Ligand Dofetilide Family
No. of Seeds 5 No. of Other Members 30
Family Centroid CFAMM00052576 Functional Category Approved Drug
Superfamily Potassium voltage-gated channel subfamily H member 2 Ligand Dofetilide Superfamily
Class Class 287

Cousin Family NamesSeedsMembers
Mineralocorticoid receptor and Androgen receptor Ligand AL-43 ... 79 235
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 11 20
Beta-1 adrenergic receptor and Beta-2 adrenergic receptor Liga... 40 90
Beta-3 adrenergic receptor Ligand BMS-196085 Family 18 72
5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 9 79
Bifunctional epoxide hydrolase 2 Inhibitor 1-(3-(3-morpholinop... 24 102
5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 8 41
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 9 28
Beta-2 adrenergic receptor and Beta-1 adrenergic receptor liga... 6 2
Beta-2 adrenergic receptor and Beta-1 adrenergic receptor liga... 3 6
Beta-3 adrenergic receptor and Beta-2 adrenergic receptor liga... 5 3
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 2 3
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 1 0
Acetylcholinesterase inhibitor AGN-PC-075N8G family 2 9
Sodium/bile acid cotransporter and Glucocorticoid receptor lig... 4 8
Substance-P receptor ligand CP 141938 family 1 0
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand Desac... 2 3
Glutamate receptor ionotropic, NMDA 1 ligand N-[4-[(2S)-3-[2-(... 2 6
Protein-S-isoprenylcysteine O-methyltransferase inhibitor 3-me... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00052576 DAP000495 Approved Drug Dofetilide
CFAMM00052577 CHEMBL99849 Bioactive AGN-PC-074TJ6
CFAMM00052593 CHEMBL323118 Bioactive AGN-PC-074TIE
CFAMM00052585 CHEMBL337696 Bioactive AGN-PC-075MI2
CFAMM00052590 CHEMBL133833 Bioactive AGN-PC-075MBJ

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

21768 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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