CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Potassium voltage-gated channel subfamily H member 2 Ligand Amiodarone Family
No. of Seeds 2 No. of Other Members 16
Family Centroid CFAMM00052608 Functional Category Approved Drug
Superfamily Potassium voltage-gated channel subfamily H member 2 Ligand Amiodarone Superfamily
Class Class 288

Cousin Family NamesSeedsMembers
Oestrogen receptor Ligand triphenyl ethylene stilbene derivati... 22 420
Beta adrenergic receptor Ligand Levobunolol Family 6 133
Sodium channel protein type 5 subunit alpha Ligand Dyclonine F... 6 174
Vitamin K epoxide reductase complex subunit 1 Inhibitor Warfar... 9 508
DNA Binder Methoxsalen Family 10 1638
Muscarinic acetylcholine receptor Ligand Flavoxate Family 9 350
Vitamin K-dependent gamma-carboxylase Inhibitor Anisindione Fa... 3 243
Multidrug resistance-associated protein 1 Inhibitor Benzbromar... 2 16
Celivarone family 1 1
Estrogen receptor beta Ligand 2-(4-hydroxy-phenyl)benzofuran-5... 5 82
cAMP-specific 3',5'-cyclic phosphodiesterase 4A Inhibitor (2,5... 1 9
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 2 14
Histamine H3 receptor Ligand A-349821 Family 49 228
Phospholipase A2 Inhibitor 3,9-dihydroxy-2,10-diprenylpterocap... 9 25
Platelet-derived growth factor receptor beta Ligand Bis(5-meth... 5 220
Cytosolic phospholipase A2 Inhibitor [6,3''']biflavone Family 5 5
Cannabinoid receptor 2 Ligand 2-(2-methoxybenzyl)-3h-benzo[f]c... 6 32
Kappa-type opioid receptor Ligand 3-(1-benzylpiperidin-4-yloxy... 24 54
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-n-... 24 73
Retinoic acid receptor RXR-alpha and Peroxisome proliferator-a... 3 17
Estrogen receptor beta and Estrogen receptor ligand AGN-PC-074... 5 4
Sodium- and chloride-dependent glycine transporter 1 inhibitor... 2 1
Thyroid hormone receptor beta and Thyroid hormone receptor alp... 1 1
ALK tyrosine kinase receptor ligand SureCN898429 family 3 0
Acetylcholinesterase and Cholinesterase inhibitor [2-[3-[7-[be... 2 0
NP 6-(4-ethoxyphenyl)-1,3-dimethyl-4-oxo-4h-cyclohepta[c]furan... 13 3
1,3-dimethylcyclohepta[c]furan-8-one NP 8-hydroxy-6-(4-methoxy... 10 0
5,6-dihydro-4H-furo[2',3':3,4]cyclohepta[1,2-b][1]benzofuran N... 3 0


External ID

Functional Category

Molecule Name

CFAMM00052608 DAP000496 Approved Drug Amiodarone
CFAMM00052612 DNCL001883 Clinical Trial Drug ATI-2042

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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