CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Sodium channel protein type 1 subunit alpha Ligand Phenacemide Family
No. of Seeds 5 No. of Other Members 6
Family Centroid CFAMM00052652 Functional Category Approved Drug with Human Metabolite
Superfamily Sodium channel protein type 1 subunit alpha Ligand Phenacemide Superfamily
Class Class 292

Cousin Family NamesSeedsMembers
Gamma-aminobutyric acid receptor subunit alpha-1 Ligand Methyl... 9 7
Sodium channel Ligand hydantoin derivative Phenytoin Family 2 25
Sodium channel protein type 5 subunit alpha Ligand Mephenytoin... 5 51
C-X-C chemokine receptor type 1 and C-X-C chemokine receptor t... 5 30
Chymase Inhibitor Phenylalanylmethane Family 1 8
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor 7-bi... 5 14
Histone deacetylase 1 Inhibitor 8-(3-benzoyl-ureido)-octanoic ... 7 13
Nuclear receptor ROR-gamma and Putative fructose-1,6-bisphosph... 1 3


External ID

Functional Category

Molecule Name

CFAMM00052652 DAP000501 Approved Drug Phenacemide
CFAMM00052651 DNC007873 Investigative Drug 6-chloro-5-phenylpyrimidine-2,4(1H,3H)-dione
CFAMM00052650 DNC007871 Investigative Drug 6-fluoro-5-phenylpyrimidine-2,4(1H,3H)-dione
CFAMM00052649 DNC007870 Investigative Drug 6-bromo-5-phenylpyrimidine-2,4(1H,3H)-dione
CFAMM00052646 DNC007874 Investigative Drug 5-benzyl-6-chloropyrimidine-2,4(1H,3H)-dione

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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Computer-aided Drug Design
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