CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Sodium channel protein type 1 subunit alpha Ligand Levetiracetam Family
No. of Seeds 7 No. of Other Members 56
Family Centroid CFAMM00052726 Functional Category Approved Drug with Human Metabolite & Natural Product
Superfamily Sodium channel protein type 1 subunit alpha Ligand Levetiracetam Superfamily
Class Class 293

Cousin Family NamesSeedsMembers
Tubulin beta chain Inhibitor Tasidotin Family 1 1
Synaptic vesicle glycoprotein 2A Inhibitor Brivaracetam Family 9 46
Beta-2 adrenergic receptor Ligand GSK642444 Family 4 10
Chymase Inhibitor Bceab Family 5 22
Dipeptidyl peptidase 4 Inhibitor Fe 999011 Family 10 45
Neutrophil collagenase Inhibitor 3-amino-azacyclotridecan-2-on... 1 17
Dipeptidyl peptidase 4 and Seprase Inhibitor N-alkyl Gly-boro-... 6 11
Dipeptidyl peptidase 4 Inhibitor (s)-pyrrolidin-2-yl(thiazolid... 1 3
Dipeptidyl peptidase 4 and Seprase Inhibitor N-alkyl Gly-boro-... 6 4
Dipeptidyl peptidase 4 Inhibitor (s)-pyrrolidin-1-yl(pyrrolidi... 2 8
C-C chemokine receptor type 2 Ligand (s)-3-(2',2'-dimethyl-pro... 1 3
Chymotrypsin-like elastase family member 1 Inhibitor Acetyl-al... 3 12
Tripeptidyl-peptidase 2 Inhibitor (2s)-aminobutyryl-(r)-pipeco... 2 15
Dipeptidyl peptidase 4 Inhibitor N-alkyl Gly-boro-pro Derivati... 2 8
Dipeptidyl peptidase 4 and Seprase Inhibitor N-alkyl Gly-boro-... 4 4
Dipeptidyl peptidase 2 and Dipeptidyl peptidase 9 inhibitor [(... 5 3
Prothrombin inhibitor [1-[[(2S)-1-acetylpyrrolidine-2-carbonyl... 1 0
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 3 0
Dipeptidyl peptidase 9 and Dipeptidyl peptidase 8 inhibitor (2... 1 0
Prolyl endopeptidase inhibitor SureCN3280014 family 1 1
Piperidines Metabolite 3-Amino-2-piperidone Family 2 2
Peptides Metabolite L-prolyl-L-glycine Family 1 3
Alkylamines Metabolite apo-[3-methylcrotonoyl-CoA:carbon-dioxi... 1 1


External ID

Functional Category

Molecule Name

CFAMM00052726 DAP000502 Approved Drug Levetiracetam
CFAMM00052720 DNC013238 Investigative Drug (2S)-aminobutyryl-L-proline n-butylamide
CFAMM00052719 DNC013239 Investigative Drug (2S)-aminobutyryl-L-proline n-propylamide
CFAMM00052699 DNC013245 Investigative Drug (2S)-aminobutyryl-L-prolinamide
CFAMM00052698 DNC013244 Investigative Drug L-norvalyl-L-prolinamide
CFAMM00052722 DNC013235 Investigative Drug (2S)-aminobutyryl-L-proline (R)-sec-butylamide
CFAMM00052728 DNC013237 Investigative Drug (2S)-aminobutyryl-L-proline n-pentylamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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