CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Voltage-gated sodium channel Ligand Riluzole Family
No. of Seeds 1 No. of Other Members 17
Family Centroid CFAMM00055130 Functional Category Approved Drug
Superfamily Voltage-gated sodium channel Ligand Riluzole Superfamily
Class Class 310

Cousin Family NamesSeedsMembers
Carbonic anhydrase Inhibitor Ethoxzolamide Family 2 42
Arachidonate 5-lipoxygenase Inhibitor 1-(4-methoxyphenyl)-3-(4... 2 1
Sodium channel protein type 5 subunit alpha Ligand Lubeluzole ... 3 12
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 6-hydr... 15 26
Insulin receptor ligand 4-[(6-methoxy-3-methyl-1,3-benzothiazo... 1 1
Vascular endothelial growth factor receptor 2 and Angiopoietin... 1 0
Luciferin 4-monooxygenase and Ras-related protein Rab-9A inhib... 2 1
Urokinase-type plasminogen activator inhibitor AGN-PC-01XMBP f... 3 7
Protein-cysteine N-palmitoyltransferase porcupine inhibitor N-... 4 1


External ID

Functional Category

Molecule Name

CFAMM00055130 DAP000527 Approved Drug Riluzole

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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