CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFAD393
Family Name Insulin receptor Ligand Insulin, Porcine Family
No. of Seeds 61 No. of Other Members 205
Family Centroid CFAMM00055277 Functional Category Approved Drug with Human Metabolite
Superfamily Peptide hormone receptor bindng peptide Superfamily
Class Class 20

Cousin Family NamesSeedsMembers
Leutinizing-hormone-releasing hormone inhibitor peptide Leupro... 43 911
Gonadotropin-releasing hormone receptor Ligand decapeptide ana... 9 162
Epidermal Growth Factor family 111 209
Parathyroid hormone/parathyroid hormone-related peptide recept... 55 256
Somatostatin receptor type 2 ligand octapeptide Octreotide Family 27 172
Insulin-degrading enzyme inhibitor cyclic polypeptide Bacitrac... 30 259
Gastrin/cholecystokinin type B receptor ligand oligopeptide Ce... 35 209
Renin Inhibitor Remikiren Family 100 126
Somatostatin receptor type 2 ligand octapeptide Lanreotide Family 93 156
ostatin receptor 5 Ligand Pasireotide Diaspartate Family 11 151
CBP-501 family 7 8
AEZS-108 family 5 2
Eluxadoline family 4 85
Cholecystokinin receptor type A Ligand A-71378 Family 77 23
Renin Inhibitor Enalkiren Family 56 44
Caspase-9 Inhibitor Z-lehd-fmk Family 1 0
5-hydroxytryptamine receptor 3A and Alpha-2A adrenergic recept... 31 24
Renin Inhibitor (h-261)boc-his-pro-phe-his-leu(oh)-val-ile-his... 33 41
Cathepsin B and Cathepsin K Inhibitor Z-ala-leu-his-agly-ile-v... 3 2
Renin Inhibitor Sul-pro-phe-n-mehis-lva-ile-amp Family 47 54
Delta-type opioid receptor and Gastrin/cholecystokinin type B ... 19 0
Melanocortin receptor Ligand Ac-his-dnal(2)-arg-trp-nh2 Family 112 67
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 50 17
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand Ac-... 38 60
Type-1 angiotensin II receptor Ligand [sar1,tdf3]angii Family 135 2
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 18 72
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 13 15
Melanocortin receptor Ligand Ac-his-dphe(3,4-dicl)-arg-trp-nh2... 10 14
Somatostatin receptor type 1 and Somatostatin receptor type 2 ... 46 0
Bombesin receptor subtype-3 and Gastrin-releasing peptide rece... 42 7
Pol polyprotein inhibitor Hydroxyethylene deriv. 12 family 13 10
Protein farnesyltransferase subunit beta and Protein farnesylt... 3 0
Lysosomal Pro-X carboxypeptidase inhibitor N-[(2S)-1-[(2S)-2-(... 1 0
Renin inhibitor propan-2-yl (3R)-2-hydroxy-3-[[(2S)-3-(1H-imid... 4 0
Pol polyprotein and Renin inhibitor U-75875 family 12 1
Placenta growth factor inhibitor CHEMBL1689479 family 4 1
Pol polyprotein inhibitor propan-2-yl N-[(2S)-1-[[(2S,3S,5R)-3... 6 2
Prothrombin and Cationic trypsin inhibitor (2S)-1-[(2R)-3,3-di... 5 9
C-C chemokine receptor type 5 ligand (2R)-2-[(3S,4S)-3-[[4-(2-... 5 0
C-C chemokine receptor type 5 ligand AC1MHRXO family 5 1
Renin inhibitor tert-butyl N-[(2S)-1-[[(2S)-1-[[(2S,3S,5S)-5-(... 2 0
KiSS-1 receptor ligand (2S)-N-[(2S)-1-[[(2S)-4-amino-1-[[(2S)-... 3 0
Melanocyte-stimulating hormone receptor and Melanocortin recep... 1 0
Renin inhibitor tert-butyl N-[(2S)-1-[[(2S)-1-[[(1R,2S)-3-cycl... 3 0
Pol polyprotein and Protease inhibitor 161186-51-2 family 5 0
Renin inhibitor (2R)-2-benzyl-N-[(2S)-1-[[(2S,3R,4S)-1-cyclohe... 6 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 4 3
Melanocyte-stimulating hormone receptor and Melanocortin recep... 1 0
Neuropeptide Y receptor type 2 ligand CHEMBL411765 family 1 0
Epidermal growth factor receptor ligand CHEMBL437469 family 1 0
Growth hormone secretagogue receptor type 1 ligand CHEMBL52599... 1 0
E3 ubiquitin-protein ligase Mdm2 and Protein Mdm4 inhibitor CH... 2 1
Sphingosine 1-phosphate receptor 1 ligand (2S)-2-[[2-(1H-imida... 4 7
Glucagon receptor ligand CHEMBL267876 family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00055357 DAP000541 Approved Drug Lepirudin
CFAMM00055308 DNAP001347 Approved Drug Desirudin
CFAMM00055356 DAP001091 Approved Drug Insulin-glargine
CFAMM00055420 DAP000802 Approved Drug Insulin recombinant
CFAMM00055355 DAP001090 Approved Drug Insulin-detemir
CFAMM00055354 DAP001092 Approved Drug Insulin-aspart
CFAMM00055277 DAP001089 Approved Drug Insulin, porcine
CFAMM00055257 DNAP001546 Approved Drug Elcatonin
CFAMM00055349 DNAP001389 Approved Drug Human neutral insulin
CFAMM00055372 DAP001302 Approved Drug Salmon Calcitonin
CFAMM00055295 DAP000822 Approved Drug Insulin-lispro
CFAMM00055334 CHEMBL507480 Bioactive CHEMBL507480
CFAMM00055364 CHEMBL2370450 Bioactive CHEMBL2370450
CFAMM00055253 CHEMBL525028 Bioactive CHEMBL525028
CFAMM00055406 CHEMBL524852 Bioactive CHEMBL524852
CFAMM00055434 CHEMBL525258 Bioactive CHEMBL525258
CFAMM00055363 CHEMBL2370451 Bioactive CHEMBL2370451
CFAMM00055524 CHEMBL2304309 Bioactive CHEMBL2304309
CFAMM00055433 CHEMBL445530 Bioactive CHEMBL445530
CFAMM00055497 CHEMBL500227 Bioactive CHEMBL500227
CFAMM00055503 CHEMBL385308 Bioactive CHEMBL385308
CFAMM00055529 CHEMBL499781 Bioactive CHEMBL499781
CFAMM00055469 CHEMBL265167 Bioactive CHEMBL265167
CFAMM00055482 CHEMBL498867 Bioactive CHEMBL498867
CFAMM00055431 CHEMBL505046 Bioactive CHEMBL505046
CFAMM00055367 CHEMBL2370455 Bioactive CHEMBL2370455
CFAMM00055269 CHEMBL1893324 Bioactive CHEMBL1893324
CFAMM00055343 CHEMBL2418879 Bioactive CHEMBL2418879
CFAMM00055408 CHEMBL506133 Bioactive CHEMBL506133
CFAMM00055514 CHEMBL219499 Bioactive CHEMBL219499
CFAMM00055282 CHEMBL524471 Bioactive CHEMBL524471
CFAMM00055387 CHEMBL1090970 Bioactive CHEMBL1090970
CFAMM00055261 CHEMBL526899 Bioactive CHEMBL526899
CFAMM00055335 CHEMBL509368 Bioactive CHEMBL509368
CFAMM00055507 CHEMBL525392 Bioactive CHEMBL525392
CFAMM00055365 CHEMBL2370453 Bioactive CHEMBL2370453
CFAMM00055281 DCL000936 Clinical Trial Drug Pramlintide
CFAMM00055300 DNCL001834 Clinical Trial Drug Aviptadil
CFAMM00055368 DNCL002885 Clinical Trial Drug LY2605541
CFAMM00055283 DCL001033 Clinical Trial Drug Vasoactive intestinal peptide
CFAMM00055303 DNCL001702 Clinical Trial Drug Forigerimod
CFAMM00055435 DNC004573 Investigative Drug CGNLSTCBLGTYTQDFNKFHZYPQTAIGVGAP-amide
CFAMM00055443 DNC007903 Investigative Drug PYY(3-36)
CFAMM00055314 DNC005996 Investigative Drug Bbs-Arg-(D-Pip)-Gly-(SPHYEKVS)-Gly-Hir
CFAMM00055340 DNC004600 Investigative Drug CGNLSTCMLGTYTQDFNPKHTFPQTAIGVGAP-amide
CFAMM00055525 DNC008886 Investigative Drug SYN-1327
CFAMM00055478 DNC004597 Investigative Drug CSNLSTCVLGKLSQELHKLQTYPRTNTGSGTP-amide
CFAMM00055398 DNC004587 Investigative Drug CGNLSTCMLGTYTQDFNKFHTFPQTAIGVGAP-amide
CFAMM00055511 DNC014780 Investigative Drug Ac-HSDAVFTDQYTRLRKQVAAKKYLQSIKQKRYC
CFAMM00055397 DNC004585 Investigative Drug CGNLSTCMLGTYTQDFNKPHTFPQTAIGVGAP-amide
CFAMM00055285 DNC012739 Investigative Drug CGNLSTCMLGTYTQDFc[DKFHO]FPQTAIGVGAP-amide
CFAMM00055516 DNC004578 Investigative Drug CSNLSTCVLGKLSQELNKLHBYPRTNTGSGTP-amide
CFAMM00055330 DNC000208 Investigative Drug Amylin
CFAMM00055515 DNC004574 Investigative Drug CGNLSTCBLGTYTQDF[DKFHO]YPQTAIGVGAP-amide
CFAMM00055402 DNC004582 Investigative Drug CGNLSTCMLGTYTQDFc[DKFHK]FPQTAIGVGAP-amide
CFAMM00055268 DNC009006 Investigative Drug NEUROPEPTIDE-Y
CFAMM00055494 DNC010605 Investigative Drug ANGIOTENSIN II
CFAMM00055401 DNC004580 Investigative Drug CGNLSTCMLGTYTQDFNPFHTFPQTAIGVGAP-amide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

21767 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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