CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFAD402
Family Name 3-hydroxy-3-methylglutaryl-coenzyme A reductase Inhibitor Atorvastatin Family
No. of Seeds 3 No. of Other Members 24
Family Centroid CFAMM00056929 Functional Category Approved Drug
Superfamily 3-hydroxy-3-methylglutaryl-coenzyme A reductase Inhibitor Atorvastatin Superfamily
Class Class 327

Cousin Family NamesSeedsMembers
3-hydroxy-3-methylglutaryl-coenzyme A reductase Inhibitor Fluv... 6 53
3-hydroxy-3-methylglutaryl-coenzyme A reductase Inhibitor Stat... 5 21
3-hydroxy-3-methylglutaryl-coenzyme A reductase Inhibitor PF-3... 6 1
3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor Sure... 2 6
3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor (3R,... 3 3
3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor Sure... 2 5
3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor Sure... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00056929 DAP000553 Approved Drug Atorvastatin
CFAMM00056918 CHEMBL333687 Bioactive Atorvastatin lactone
CFAMM00056932 DNC013452 Investigative Drug atorvastatin calcium

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

21767 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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