CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Acetylcholinesterase Inhibitor Physostigmine Family
No. of Seeds 13 No. of Other Members 155
Family Centroid CFAMM00058089 Functional Category Approved Drug with Natural Product
Superfamily Acetylcholinesterase Inhibitor Physostigmine Superfamily
Class Class 334

Cousin Family NamesSeedsMembers
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 1 2
Histamine H3 receptor and Histamine receptor H3 ligand 1-[4-[3... 2 0
Cholinesterase and Acetylcholinesterase inhibitor [(3aR,8bS)-4... 1 0
Acyl-CoA:cholesterol acyltransferase inhibitor SureCN9818603 f... 2 2
D(2) dopamine receptor and D(3) dopamine receptor ligand 1-(3-... 2 0


External ID

Functional Category

Molecule Name

CFAMM00058089 DAP000561 Approved Drug Physostigmine
CFAMM00058194 DNC011172 Investigative Drug ETHYLPHENSERINE
CFAMM00058114 DNC000505 Investigative Drug Cymserine
CFAMM00058060 DNC003868 Investigative Drug PHENSERINE
CFAMM00058193 DNC011174 Investigative Drug GANSTIGMINE
CFAMM00058093 DNC013072 Investigative Drug GENESERINE
CFAMM00058140 DNC006354 Investigative Drug TOLSERINE
CFAMM00058149 DNC011057 Investigative Drug (-)-Phenethylcymserine
CFAMM00058227 DNC004801 Investigative Drug CHF-2819
CFAMM00058121 DNC014169 Investigative Drug Physostigmine salicylate
CFAMM00058154 DNC002655 Investigative Drug MF268
CFAMM00058103 DNC003565 Investigative Drug HEPTYPHYSOSTIGMINE
CFAMM00058195 DNC011173 Investigative Drug QUILOSTIGMINE

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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