CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Acetylcholinesterase Inhibitor Edrophonium Family
No. of Seeds 7 No. of Other Members 40
Family Centroid CFAMM00058244 Functional Category Approved Drug with Natural Product
Superfamily Acetylcholinesterase Inhibitor Edrophonium Superfamily
Class Class 335

Cousin Family NamesSeedsMembers
Alpha adrenergic receptor Ligand Phentolamine Family 2 9
Acetylcholinesterase Inhibitor Neostigmine Family 4 76
Cyclooxygenase Inhibitor Acetaminophen Family 2 42
Tumor necrosis factor Inhibitor Tgaac-94 Family 6 107
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 6 131
5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 9 79
Carbonic anhydrase 14 Inhibitor 4-aminophenol Family 1 6
5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 8 41
D(2) dopamine receptor and D(3) dopamine receptor Ligand D-237... 21 56
Indoleamine 2,3-dioxygenase 1 Inhibitor 4-(ethylamino)naphthal... 10 13
Leukotriene A-4 hydrolase Inhibitor 1-[4-(4-iodophenoxy)phenyl... 5 18
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 9 28
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 21 13
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 2 9
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 1 3
Estrogen receptor and Estrogen receptor beta ligand AGN-PC-00G... 16 4
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 14 12
Mitogen-activated protein kinase 1 and Muscarinic acetylcholin... 1 1
Survival motor neuron protein and DNA-(apurinic or apyrimidini... 1 5
Acetylcholinesterase inhibitor AGN-PC-075N8G family 2 9
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 1 2
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 11 4
Amyloid beta A4 protein inhibitor SureCN6372684 family 2 7
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 1 0
Melanin-concentrating hormone receptor 1 ligand SureCN6779516 ... 1 0
Sigma non-opioid intracellular receptor 1 and 5-hydroxytryptam... 1 0
Estrogen receptor beta and Estrogen receptor ligand (E)-3-[4-(... 1 0
5-hydroxytryptamine receptor 2A ligand AGN-PC-075M0I family 1 0
Oxysterols receptor LXR-beta and Oxysterols receptor LXR-alpha... 2 1


External ID

Functional Category

Molecule Name

CFAMM00058244 DAP000562 Approved Drug Edrophonium
CFAMM00058242 CHEMBL128610 Bioactive 3-(4,4-dimethylpiperazin-4-ium-1-yl)phenol;iodide
CFAMM00058263 CHEMBL1128 Bioactive Edrophonium chloride
CFAMM00058257 DNC014010 Investigative Drug 3-hydroxy-N,N,N-trimethylbenzenaminium iodide
CFAMM00058286 DNC013782 Investigative Drug EDROPHONIUM BROMIDE
CFAMM00058239 DNC003530 Investigative Drug 3-(4-Benzyl-piperazin-1-yl)-phenol
CFAMM00058291 DNC010444 Investigative Drug 1-(3-Hydroxyphenyl)-4-propylpiperazine

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

Last update by



48689 visits since 2014 .........


Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links


Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543