CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Adenosine deaminase Inhibitor Pentostatin Family
No. of Seeds 4 No. of Other Members 13
Family Centroid CFAMM00058396 Functional Category Approved Drug with Human Metabolite & Natural Product
Superfamily Adenosine deaminase Inhibitor Pentostatin Superfamily
Class Class 338

Cousin Family NamesSeedsMembers
Adenosine receptor A3 ligand purine nucleoside Adenosine Family 47 847
HIV reverse transcriptase inhibitor guanosine analog Didanosin... 20 166
Adenosine receptor A1 and Adenosine receptor A3 ligand (2R,3S,... 1 0
NS3 inhibitor sodium;[[[(2S,3R,4S,5S)-5-(4,8-diamino-6-iminoim... 1 0
Reverse transcriptase/RNaseH inhibitor [(2R,3R,4R,5R)-4-methox... 1 0


External ID

Functional Category

Molecule Name

CFAMM00058396 DAP000566 Approved Drug Pentostatin
CFAMM00058399 CHEMBL2368596 Bioactive (8R)-5-ethyl-3-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-8-ol
CFAMM00058394 DNC000460 Investigative Drug Coformycin
CFAMM00058407 DNC003217 Investigative Drug 6-Hydroxy-1,6-Dihydro Purine Nucleoside

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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