CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFAD423
Family Name Amine oxidase [flavin-containing] B Inhibitor Phenelzine Family
No. of Seeds 7 No. of Other Members 15
Family Centroid CFAMM00059639 Functional Category Approved Drug
Superfamily Biogenic amine receptor, re-uptake and enxyme binding amphetamine phenethylamine Superfamily
Class Class 73

Cousin Family NamesSeedsMembers
Alpha-1B adrenergic receptor ligand phenethylamine derivative ... 12 283
AMP-activated protein kinase Inhibitor Phenformin Family 5 14
Amine oxidase [flavin-containing] B Inhibitor Selegiline Family 6 26
Noradrenergic re-uptake Inhibitor Phentermine Family 2 11
Serotonin re-uptake Inhibitor Dexfenfluramine Family 6 31
Glutamate receptor AMPA subtype and Noradrenaline uptake Ligan... 9 17
Aldehyde oxidase Inhibitor Benzamidine Family 2 6
Dipeptidyl peptidase 4 Inhibitor 1-biphenyl-2-ylmethanamine Fa... 2 23
Beta-secretase 1 Inhibitor 4-(4-fluorobenzyl)piperidine Family 2 4
Histamine H3 receptor Ligand 1-[2-(2,4,6-trimethyl-phenyl)-eth... 9 15
Amine oxidase [flavin-containing] A Inhibitor 1-(2-naphthyl)-2... 4 4
Amine oxidase [flavin-containing] A Inhibitor Trans-(+/-)-2-fl... 2 0
Aminopeptidase N Inhibitor (1-amino-2-phenyl-ethyl)-phosphinic... 3 11
Amine oxidase [flavin-containing] B Inhibitor Methyl-(1,2,3,4-... 2 0
Alpha-2A adrenergic receptor and Alpha-2B adrenergic receptor ... 3 6
Sodium-dependent dopamine transporter and Sodium-dependent ser... 8 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00059639 DAP000578 Approved Drug Phenelzine
CFAMM00059628 CHEMBL538327 Bioactive AGN-PC-00D0AI
CFAMM00059634 CHEMBL534938 Bioactive AGN-PC-00BU6H
CFAMM00059648 CHEMBL536059 Bioactive AGN-PC-00AHOA
CFAMM00059633 CHEMBL553631 Bioactive AGN-PC-00EOUJ
CFAMM00059632 CHEMBL556769 Bioactive SureCN5694837
CFAMM00059645 DNC006340 Investigative Drug N'-(2-phenylallyl)hydrazine hydrochloride

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

21794 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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