CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFAD426
Family Name Angiotensin-converting enzyme inhibitor Phosphonate-containing Fosinopril Family
No. of Seeds 7 No. of Other Members 41
Family Centroid CFAMM00060153 Functional Category Approved Drug with Human Metabolite
Superfamily Angiotensin-converting enzyme inhibitor Enalapril Fosinopril Cilazapril Spirapril Superfamily
Class Class 347

Cousin Family NamesSeedsMembers
Angiotensin-converting enzyme inhibitor Dicarboxylate-containi... 16 374
Angiotensin-converting enzyme Inhibitor Spirapril Family 17 86
ATP-sensitive inward rectifier potassium channel 10 Ligand Nat... 3 233
Bacterial outer membrane Inhibitor Polymyxin B Family 17 181
Flovagatran family 12 546
Proto-oncogene tyrosine-protein kinase Src Inhibitor RU83876 F... 3 51
Beta-secretase 1 Inhibitor MMI-175 Family 30 137
Plasmepsin-1 Inhibitor SC-5003 Family 93 173
Neuromedin-K receptor Ligand PD-157672 Family 9 37
Calcitonin gene-related peptide type 1 receptor Ligand Fvptdvg... 8 8
Integrin alpha-V Inhibitor C[rgdf-(3s)-carboxymorpholine] Family 10 2
Caspase-4 and Cathepsin D Inhibitor Grassystatin A Family 24 6
Endothelin-converting enzyme 1 Inhibitor PO3 2-leu-nal-o-3k Fa... 3 26
Genome polyprotein Inhibitor Acdif-ile-cha-cys Family 37 96
Mu-type opioid receptor and Nociceptin receptor Ligand Nocicep... 35 5
Cholecystokinin receptor type A Ligand CR-1795 Family 19 41
Angiotensin-converting enzyme inhibitor (S)-1-((S)-5-benzamido... 5 2
Neprilysin and Aminopeptidase N inhibitor (2S)-2-[[(2S)-2-[[[a... 13 1
Carboxypeptidase B and Carboxypeptidase B2 inhibitor (2S)-7-am... 3 9
Renin inhibitor [(2R)-1-[[(2S,3S,5R)-6-(butylamino)-1-cyclohex... 5 4
Neprilysin inhibitor SureCN489232 family 3 9
Neprilysin and Angiotensin-converting enzyme inhibitor (2S)-2-... 5 3
Angiotensin-converting enzyme inhibitor (8S)-7-[2-[hydroxy(4-p... 1 1
Angiotensin-converting enzyme inhibitor 2-(N-[(2S)-6-amino-2-[... 2 1
Angiotensin-converting enzyme inhibitor (2S,4R)-1-[(2S)-6-amin... 3 1
Angiotensin-converting enzyme inhibitor (2S,4R)-1-[(2S)-6-amin... 6 0
Angiotensin-converting enzyme and Angiotensin-converting enzym... 1 0
Neprilysin inhibitor AGN-PC-075S5F family 1 1
Breast cancer type 1 susceptibility protein inhibitor (2S)-2-[... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00060153 DAP000582 Approved Drug Fosinopril
CFAMM00060137 CHEMBL35309 Bioactive (2S,4R)-1-[(2S)-6-amino-2-[hydroxy(4-phenylbutyl)phosphoryl]oxyhexanoyl]-4-phenylpyrrolidine-2-carboxylic acid
CFAMM00060123 CHEMBL581 Bioactive Fosinoprilat
CFAMM00060146 CHEMBL284843 Bioactive (2S,4S)-1-[(2S)-6-amino-2-[hydroxy(4-phenylbutyl)phosphoryl]oxyhexanoyl]-4-benzylpyrrolidine-2-carboxylic acid
CFAMM00060165 CHEMBL115832 Bioactive FOSINOPRIL

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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