CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFAD43
Family Name 5-alpha reductase inhibitor azasteroid derivative Finasteride family
No. of Seeds 3 No. of Other Members 30
Family Centroid CFAMM00008046 Functional Category Approved Drug with Natural Product
Superfamily 5-alpha reductase inhibitor azasteroid derivative Finasteride Superfamily
Class Class 43

Cousin Family NamesSeedsMembers
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 1 1
3-oxo-5-alpha-steroid 4-dehydrogenase 2 and 3-oxo-5-alpha-ster... 11 14
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 1 0
Histamine H3 receptor ligand Conessine analogue, 13a family 4 3
Androgen receptor ligand methyl (5aR)-6,9a,11a-trimethyl-7-oxo... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00008046 DAP000045 Approved Drug Finasteride
CFAMM00008042 CHEMBL338207 Bioactive (9aR,11aR)-9a,11a-dimethyl-1-(6-methylheptan-2-yl)-1,2,3,3a,3b,4,5,5a,6,9b,10,11-dodecahydroindeno[5,4-f]quinolin-7-one
CFAMM00008054 CHEMBL126686 Bioactive (4S,9aR,11aR)-4,9a,11a-trimethyl-1-(6-methylheptan-2-yl)-1,2,3,3a,3b,4,5,5a,6,9b,10,11-dodecahydroindeno[5,4-f]quinolin-7-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

21785 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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