CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFAD434
Family Name cAMP-specific 3',5'-cyclic phosphodiesterase 4A inhibitor xanthine derivative Dyphylline Family
No. of Seeds 3 No. of Other Members 7
Family Centroid CFAMM00061165 Functional Category Approved Drug with Natural Product
Superfamily cAMP-specific 3',5'-cyclic phosphodiesterase, TNF inhibitor xanthine derivative Superfamily
Class Class 2

Cousin Family NamesSeedsMembers
cAMP-specific 3',5'-cyclic phosphodiesterase 4A inhibitor xant... 18 210
Tumor necrosis factor inhibitor xanthine derivative Pentoxifyl... 5 69
xanthine alkaloid Theobromine family 6 10
DNA polymerase inhibitor guanosine analog Aciclovir Family 4 41
DNA polymerase Inhibitor Valaciclovir Family 2 0
UDP-N-acetylglucosamine 1-carboxyvinyltransferase Inhibitor RW... 1 0
Hypoxanthine-guanine-xanthine phosphoribosyltransferase Inhibi... 3 7
Adenosine receptor A1 Ligand 7-(3,6,9,12-tetraoxatricos-22-eny... 1 1
Purine nucleoside phosphorylase inhibitor [(3R,4S)-3-(2-amino-... 1 0
Adenosine receptor A2a and Adenosine receptor A2b ligand NSC14... 1 2
Dipeptidyl peptidase 4 inhibitor SureCN554974 family 2 1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D and cAMP-speci... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00061165 DAP000596 Approved Drug Dyphylline
CFAMM00061163 DNAP001547 Approved Drug Doxofylline
CFAMM00061168 DNC011058 Investigative Drug BETA-HYDROXYETHYL THEOPHYLLINE

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

21783 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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