CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Ceramide glucosyltransferase Inhibitor Miglustat Family
No. of Seeds 4 No. of Other Members 73
Family Centroid CFAMM00061365 Functional Category Approved Drug with Human Metabolite & Natural Product
Superfamily Ceramide glucosyltransferase Inhibitor Miglustat Superfamily
Class Class 360

Cousin Family NamesSeedsMembers
Alpha-galactosidase A and Lactase-phlorizin hydrolase Inhibito... 6 22
Glucosylceramidase Inhibitor L-isofagomine Family 3 8
Glucosylceramidase Inhibitor (2r,3s,4s,5r)-2-nonylpiperidine-3... 6 9
Lysosomal alpha-glucosidase Inhibitor (-)-uniflorine A Family 3 3
Sucrase-isomaltase, intestinal and Maltase-glucoamylase, intes... 2 2
Non-lysosomal glucosylceramidase inhibitor N-carboxynonyldeoxy... 1 3


External ID

Functional Category

Molecule Name

CFAMM00061365 DAP000609 Approved Drug Miglustat
CFAMM00061407 DAP000712 Approved Drug Miglitol
CFAMM00061429 DCL000166 Clinical Trial Drug Migalastat
CFAMM00061440 DNC004647 Investigative Drug DEOXYNOJIRIMYCIN

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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