CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Cyclooxygenase Inhibitor Ketorolac Family
No. of Seeds 3 No. of Other Members 40
Family Centroid CFAMM00065593 Functional Category Approved Drug
Superfamily Cyclooxygenase Inhibitor Ketorolac Superfamily
Class Class 365

Cousin Family NamesSeedsMembers
Integrase Inhibitor L-731,988 Family 1 4
Lethal factor Inhibitor 3-(2,5-dimethyl-1h-pyrrol-1-yl)benzoic... 2 44
Aldose reductase Inhibitor 3-(3-benzoyl-1h-pyrrol-1-yl)propano... 3 7
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 3 12
Glucagon receptor and Gastric inhibitory polypeptide receptor ... 2 5
Phospholipase A2, membrane associated inhibitor AGN-PC-075RBK ... 1 2
Glutamate carboxypeptidase 2 inhibitor 1-[(3-carboxyphenyl)met... 4 11
Glutamate receptor 4 and Glutamate receptor 2 ligand SureCN437... 4 12
Prostaglandin E synthase inhibitor 3-(4-dodecanoyl-1,5-dimethy... 2 0
Botulinum neurotoxin type A inhibitor N-(7-aminoheptyl)-1-benz... 2 0


External ID

Functional Category

Molecule Name

CFAMM00065593 DAP000618 Approved Drug Ketorolac
CFAMM00065585 DAP000777 Approved Drug Tolmetin
CFAMM00065568 CHEMBL1201124 Bioactive Ketorolac tromethamine

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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