CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Cyclooxygenase Inhibitor Diclofenac Family
No. of Seeds 6 No. of Other Members 37
Family Centroid CFAMM00066805 Functional Category Approved Drug with Human Metabolite & Natural Product
Superfamily Cyclooxygenase Inhibitor Diclofenac Superfamily
Class Class 367

Cousin Family NamesSeedsMembers
Prostaglandin G/H synthase 1 Inhibitor Mesalazine Family 2 30
Prostaglandin G/H synthase 2 Inhibitor Mefenamic Acid Family 7 137
Cyclooxygenase Inhibitor Meclofenamic Acid Family 4 11
Serum albumin Inhibitor Iodipamide Family 2 23
Glycogen synthase kinase-3 beta Inhibitor I-5 Family 1 8
Neuraminidase Inhibitor 4-(acetylamino)-3-amino Benzoic Acid F... 2 27
Tyrosine-protein phosphatase non-receptor type 1 Ligand 2-(oxa... 3 11
Bifunctional epoxide hydrolase 2 Inhibitor 4-(3-adamantan-1-yl... 3 12
Acetylcholinesterase Inhibitor 3-(2,5-dioxo-pyrrolidin-1-yl)-b... 2 4
Dihydroorotate dehydrogenase (quinone), mitochondrial inhibito... 2 0
Aldo-keto reductase family 1 member C3 and Aldo-keto reductase... 1 0
2-(4-aminophenyl)butanedioate NP ZINC31165273 Family 4 12
2-oxo-1H-quinoline-4-carboxylate NP ZINC19735150 Family 5 4
Putative NP ZINC19701878 Family 4 2


External ID

Functional Category

Molecule Name

CFAMM00066806 DAP000970 Approved Drug Lumiracoxib
CFAMM00066805 DAP000620 Approved Drug Diclofenac
CFAMM00066803 DNC009847 Investigative Drug 2-(2-(2-chlorophenylamino)phenyl)acetic acid
CFAMM00066802 DNC009848 Investigative Drug 2-(2-(2-fluorophenylamino)phenyl)acetic acid
CFAMM00066835 DNC005898 Investigative Drug DICLOFENAC SODIUM
CFAMM00066804 DNC009846 Investigative Drug 2-(2-(2,5-dichlorophenylamino)phenyl)acetic acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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