CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name 14-alpha sterol demethylase Inhibitor Terconazole Family
No. of Seeds 4 No. of Other Members 46
Family Centroid CFAMM00067914 Functional Category Approved Drug with Human Metabolite
Superfamily 14-alpha sterol demethylase Inhibitor Terconazole Superfamily
Class Class 373

Cousin Family NamesSeedsMembers
14-alpha sterol demethylase inhibitor imidazole derivative Mi... 6 59
14-alpha sterol demethylase Inhibitor Posaconazole Family 1 5
Cytochrome P450 2D6 and Cytochrome P450 3A4 Inhibitor 2-[3-(4-... 7 128
Aromatase inhibitor AGN-PC-075MOK family 1 4
Sphingosine 1-phosphate receptor 1 ligand (2S)-2-[[2-(1H-imida... 4 7
Beta-2 adrenergic receptor and Beta-3 adrenergic receptor liga... 4 6
Beta-2 adrenergic receptor and Beta-1 adrenergic receptor liga... 6 0
Melanocortin receptor 4 ligand (3R)-N-[(2R)-3-(4-chlorophenyl)... 1 0
Heme oxygenase 1 inhibitor 1-[[(2R,4R)-2-[2-(4-chlorophenyl)et... 4 13


External ID

Functional Category

Molecule Name

CFAMM00067914 DAP000629 Approved Drug Terconazole
CFAMM00067950 DAP000630 Approved Drug Ketoconazole
CFAMM00067949 DAP000631 Approved Drug Itraconazole
CFAMM00067961 DNCL002947 Clinical Trial Drug CORT001

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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