CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFAD465
Family Name Peptide deformylase, mitochondrial Inhibitor Proguanil Family
No. of Seeds 8 No. of Other Members 46
Family Centroid CFAMM00068212 Functional Category Approved Drug with Human Metabolite
Superfamily Peptide deformylase, mitochondrial Inhibitor Proguanil Superfamily
Class Class 376

Cousin Family NamesSeedsMembers
Alpha-2 adrenergic receptor Ligand Clonidine Family 4 20
Gamma-aminobutyric acid A receptor Ligand ELB-139 Family 1 3
Metabotropic glutamate receptor 5 Ligand Mcn3377 Family 1 12
Glutamate receptor ionotropic, NMDA 2A and Glutamate receptor ... 14 78
Bifunctional epoxide hydrolase 2 Inhibitor 1-(3-chloro-phenyl)... 5 50
Carbonic anhydrase 2 and Carbonic anhydrase 4 Inhibitor 1-(3,4... 2 9
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 4 18
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 3 34
Bifunctional epoxide hydrolase 2 Inhibitor 1-phenyl-3-(1-propi... 22 183
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 6 45
DNA topoisomerase Inhibitor 6-(3-iodo-phenylamino)-1h-pyrimidi... 2 5
5-hydroxytryptamine receptor 3E and 5-hydroxytryptamine recept... 1 0
5-hydroxytryptamine receptor 2C ligand SureCN5872545 family 3 0
Bifunctional dihydrofolate reductase-thymidylate synthase inhi... 5 3
Bifunctional dihydrofolate reductase-thymidylate synthase and ... 1 8
Bifunctional dihydrofolate reductase-thymidylate synthase inhi... 1 1
Bloom syndrome protein and Prelamin-A/C inhibitor DCEBIO family 1 1
Dihydrofolate reductase inhibitor AC1MBSH5 family 1 0
Calcium/calmodulin-dependent protein kinase type II subunit de... 1 0
Nitric oxide synthase, brain inhibitor AC1PDD8N family 5 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00068226 DAP001326 Approved Drug Chlorhexidine
CFAMM00068205 DAP001464 Approved Drug Chlorproguanil
CFAMM00068212 DAP000634 Approved Drug Proguanil
CFAMM00068228 CHEMBL90703 Bioactive AGN-PC-074P6P
CFAMM00068221 CHEMBL93484 Bioactive AC1L1TU0
CFAMM00068182 CHEMBL90292 Bioactive AGN-PC-074P6M
CFAMM00068180 CHEMBL92047 Bioactive AC1L9LBJ
CFAMM00068187 DNC000494 Investigative Drug Cycloguanil

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

21767 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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