CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFAD468
Family Name Dihydropterin pyrophosphokinase-dihydropteroate synthase Inhibitor Dapsone Family
No. of Seeds 9 No. of Other Members 88
Family Centroid CFAMM00068699 Functional Category Approved Drug with Human Metabolite & Natural Product
Superfamily Dihydropterin pyrophosphokinase-dihydropteroate synthase Inhibitor Dapsone Superfamily
Class Class 379

Cousin Family NamesSeedsMembers
Mannose-6-phosphate isomerase Inhibitor Sulfacetamide Family 19 117
Mannose-6-phosphate isomerase Inhibitor Sulfoxone Family 3 20
Mannose-6-phosphate isomerase Inhibitor Sulfanilamide Family 4 8
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 4-hydr... 3 3
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 3-chlo... 2 12
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 4-amin... 2 5
Reverse transcriptase Inhibitor 2-amino-6-(naphthalene-1-sulfo... 3 6
Carbonic anhydrase 2 Inhibitor 3-nitro-benzenesulfonamide Family 3 19
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 4-isot... 1 2
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 4-[2-(... 5 72
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 3-(3-p... 7 17
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 4-amin... 3 7
Reverse transcriptase Inhibitor 1-nitro-2-(2-nitrophenylsulfon... 3 8
5-hydroxytryptamine receptor 6 Ligand 4-(4-benzenesulfonamidop... 4 5
5-hydroxytryptamine receptor 6 Ligand N-(3-(2-aminoethyl)pheny... 8 25
Carbonic anhydrase 2 and Prostaglandin G/H synthase 2 Inhibito... 8 10
Carbonic anhydrase 2 and Carbonic anhydrase 9 Inhibitor 3-((4-... 5 4
Reverse transcriptase Inhibitor 2-amino-6-(2-cyano-benzenesulf... 16 2
Prostaglandin G/H synthase 1 Inhibitor 4-amino-n-(2-chlorophen... 2 3
Prostaglandin G/H synthase 1 and Prostaglandin G/H synthase 2 ... 2 2
Gamma-aminobutyric acid receptor Ligand Toluene-1-diazonium-3-... 1 1
Carbonic anhydrase Inhibitor 4-amino-3-fluoro-5-iodobenzenesul... 1 0
Thyroid hormone receptor beta and Beta-lactamase ligand CHEMBL... 1 3
Carbonic anhydrase 9 and Carbonic anhydrase 2 inhibitor AGN-PC... 6 2
Carbonic anhydrase 2 inhibitor 4-(3-hydroxypropylsulfanyl)-3-n... 4 1
Beta-lactamase inhibitor 3-(4-BENZENESULFONYL-THIOPHENE-2-SULF... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00068699 DAP000637 Approved Drug Dapsone
CFAMM00068640 CHEMBL23922 Bioactive ST50718916
CFAMM00068587 CHEMBL2164732 Bioactive 4-[[4-(sulfamoylamino)phenyl]sulfonylamino]benzenesulfonamide
CFAMM00068685 CHEMBL14182 Bioactive 3-[(4-aminophenyl)sulfonylamino]benzenesulfonamide
CFAMM00068590 CHEMBL269122 Bioactive 4-amino-N-(4-sulfamoylphenyl)benzenesulfonamide
CFAMM00068641 DNC010196 Investigative Drug 4-((4-aminophenyl)diazenyl)benzenesulfonamide
CFAMM00068599 DNC006792 Investigative Drug N-(3-aminophenyl)benzenesulfonamide
CFAMM00068613 DNC005757 Investigative Drug 4-Benzenesulfonylamino-benzenesulfonamide
CFAMM00068649 DNC013255 Investigative Drug 4-amino-N-(4-iodophenyl)benzenesulfonamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

21767 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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