CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFAD470
Family Name Dipeptidyl peptidase 4 Inhibitor Sitagliptin Family
No. of Seeds 6 No. of Other Members 4
Family Centroid CFAMM00068733 Functional Category Approved Drug
Superfamily chemokine receptor ligand Maraviroc, Dipeptidyl peptidase inhibitor superSitagliptin family
Class Class 214

Cousin Family NamesSeedsMembers
C-C chemokine receptor type 5 Ligand Maraviroc Family 29 81
C-C chemokine receptor type 5 ligand N-[(1S)-3-[4-(3-methyl-5-... 2 0
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 2 inhibitor (3... 2 0
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor (3... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00068733 DAP000639 Approved Drug Sitagliptin
CFAMM00068731 CHEMBL393336 Bioactive Sitagliptin phosphate
CFAMM00068738 CHEMBL536999 Bioactive (3R)-3-amino-1-[8-(2,2,2-trifluoroethyl)-3-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one;hydrochloride
CFAMM00068726 CHEMBL556979 Bioactive 2-[7-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl]-3-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-8-yl]-N,N-dimethylacetamide;hydrochloride
CFAMM00068734 CHEMBL536312 Bioactive (3R)-3-amino-1-[8-[[3,5-bis(trifluoromethyl)phenyl]methyl]-3-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one;hydrochloride
CFAMM00068732 DNC006919 Investigative Drug ABT-341

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

21767 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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