CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name DNA polymerase Inhibitor Cytarabine Family
No. of Seeds 5 No. of Other Members 62
Family Centroid CFAMM00068841 Functional Category Approved Drug with Human Metabolite & Natural Product
Superfamily DNA polymerase Inhibitor Cytarabine Superfamily
Class Class 382

Cousin Family NamesSeedsMembers
Thymidylate synthase Inhibitor Capecitabine Family 1 6
cytosine arabinose derivative Cytarabine Family 6 11
cytosine arabinose derivative Enocitabine Family 3 4
DNA polymerase Inhibitor Ddctp Family 1 1
Reverse transcriptase/RNaseH inhibitor AC1LA4TB family 2 0
P2Y purinoceptor 6 and P2Y purinoceptor 4 inhibitor bis[[(2R,3... 1 2
DNA polymerase alpha catalytic subunit and DNA polymerase subu... 1 0
Putative NP ZINC04024171 Family 4 0


External ID

Functional Category

Molecule Name

CFAMM00068807 DAP001246 Approved Drug Gemcitabine
CFAMM00068841 DAP000644 Approved Drug Cytarabine
CFAMM00068815 DAP000703 Approved Drug Zalcitabine
CFAMM00068779 DNC003089 Investigative Drug 2'-Deoxycytidine-5'-Monophosphate
CFAMM00068763 DNC014595 Investigative Drug DEOXYCYTIDINE

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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