CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name DNA topoisomerase 2-beta and DNA topoisomerase 4 subunit A Inhibitor Gemifloxacin Family
No. of Seeds 3 No. of Other Members 40
Family Centroid CFAMM00069074 Functional Category Approved Drug
Superfamily DNA topoisomerase 2-beta and DNA topoisomerase 4 subunit A Inhibitor Gemifloxacin Superfamily
Class Class 385

Cousin Family NamesSeedsMembers
DNA topoisomerase 2-beta Inhibitor Nalidixic Acid Family 2 5
Prostaglandin G/H synthase 2 Inhibitor Niflumic Acid Family 7 119
Topoisomerase IV Inhibitor ABT-492 Family 1 6
Glycogen synthase kinase-3 beta inhibitor 5-amino-1-cyclopropy... 3 14
DNA polymerase III PolC-type inhibitor SureCN6783958 family 1 0
Dipeptidyl peptidase 4 inhibitor 7-[(3R,4R)-3-amino-4-(3,4-dic... 1 0


External ID

Functional Category

Molecule Name

CFAMM00069094 DAP000652 Approved Drug Trovafloxacin
CFAMM00069074 DAP000851 Approved Drug Gemifloxacin
CFAMM00069088 DAP001000 Approved Drug Enoxacin

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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