CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name DNA binder anthracycline analog Doxorubicin family
No. of Seeds 9 No. of Other Members 32
Family Centroid CFAMM00008257 Functional Category Approved Drug with Human Metabolite & Natural Product
Superfamily Binder Superfamily
Class Class 47

Cousin Family NamesSeedsMembers
Heat shock protein 90, putative Inhibitor Cromoglicate Family 14 2827
D-alanyl-D-alanine carboxypeptidase Inhibitor B-lactams Family 59 1364
DNA Binder Amrubicin Hcl Family 3 0
Hidrosmin family 14 61
Ipriflavone family 62 2480
Rotenone family 16 107
Chromomycin A3 family 7 14
Leukotriene B4 receptor 1 Ligand LY293111 Family 24 79
Interleukin-1 beta Inhibitor Diacerein Family 3 77
Glucose-6-phosphate translocase Inhibitor Mumbaistatin Family 3 11
Oestrogen receptor and Estrogen receptor beta Ligand 3,8-dihyd... 20 57
MO15-related protein kinase Pfmrk Inhibitor WR-289012 Family 2 17
Indoleamine 2,3-dioxygenase 1 Inhibitor 2-hydroxygarvin A Family 2 2
Voltage-dependent N-type calcium channel subunit alpha-1B Liga... 1 6
Multidrug resistance-associated protein 1 inhibitor (2S)-2-ami... 1 1
Acenes Metabolite Musanolone D Family 2 1
6a,7,8,12a-tetrahydroxy-3-methyl-2,3,4,5,6,7-hexahydrobenzo[a]... 6 0


External ID

Functional Category

Molecule Name

CFAMM00008267 DAP000050 Approved Drug Idarubicin
CFAMM00008337 DAP000650 Approved Drug Valrubicin
CFAMM00008286 DAP000788 Approved Drug Daunorubicin
CFAMM00008247 DNAP001485 Approved Drug Pirarubicin
CFAMM00008266 DAP001342 Approved Drug Aclarubicin
CFAMM00008258 DAP000193 Approved Drug Epirubicin
CFAMM00008257 DAP000192 Approved Drug Doxorubicin
CFAMM00008238 DNC000159 Investigative Drug AD 198
CFAMM00008253 DNC000163 Investigative Drug Adriamycin

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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