CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFAD480
Family Name Farnesyl pyrophosphate synthase Inhibitor Risedronate Family
No. of Seeds 4 No. of Other Members 28
Family Centroid CFAMM00069828 Functional Category Approved Drug
Superfamily Farnesyl pyrophosphate synthase Inhibitor Risedronate Superfamily
Class Class 387

Cousin Family NamesSeedsMembers
Nicotinic acetylcholine receptor Ligand Nicotine Family 14 686
Thromboxane A2 receptor Ligand Ridogrel Family 7 83
Histamine H1 receptor Ligand Pheniramine Family 10 380
Histamine H1 receptor Ligand Triprolidine Family 19 316
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor Ethion... 5 68
Diacylglycerol O-acyltransferase 2 and Hydroxycarboxylic acid ... 4 45
Cytochrome P450 11B1, mitochondrial and Aromatase Inhibitor 3-... 2 11
Cytochrome P450 11B1, mitochondrial and Aromatase Inhibitor 3-... 14 22
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 13 26
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 1-methyl-1h... 6 24
Farnesyl pyrophosphate synthase Inhibitor Piridronic Acid Family 3 14
Acetylcholinesterase and Cholinesterase Inhibitor 1,9-bis(pyri... 8 38
Cytochrome P450 11B1, mitochondrial Inhibitor Metyrapol Family 3 41
Cytochrome P450 11B1, mitochondrial Inhibitor 2-methyl-1,2-di-... 8 15
Metabotropic glutamate receptor 5 Ligand 3-m-tolyl-1,5-naphthy... 6 10
Metabotropic glutamate receptor 5 Ligand 5-((6-methylpyridin-2... 14 22
Geranylgeranyl pyrophosphate synthase and Farnesyl pyrophospha... 1 0
Squalene synthase inhibitor AGN-PC-00ONKT family 1 0
Pyridines and Derivatives Metabolite Venoterpine Family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00069828 DAP000658 Approved Drug Risedronate
CFAMM00069829 CHEMBL192342 Bioactive bisphosphonate, 46
CFAMM00069844 DNC000740 Investigative Drug Homorisedronate
CFAMM00069823 DNC008432 Investigative Drug NE-10575

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

21767 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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