CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFAD484
Family Name Fatty-acid amide hydrolase 1 Inhibitor Propofol Family
No. of Seeds 5 No. of Other Members 428
Family Centroid CFAMM00070089 Functional Category Approved Drug with Human Metabolite & Natural Product
Superfamily Fatty-acid amide hydrolase 1 Inhibitor Propofol Superfamily
Class Class 391

Cousin Family NamesSeedsMembers
Cannabinoid receptor 1 Ligand Marinol Family 32 454
Muscarinic acetylcholine receptor M3 Ligand Tolterodine Family 8 171
Estrogen receptor beta Ligand Conjugated Estrogens Family 12 210
Tyrosinase Inhibitor Monobenzone Family 6 197
Oestrogen receptor ligand steroid Estradiol Family 18 147
Oestrogen receptor ligand Dienestrol Family 35 440
Noradrenergic re-uptake Inhibitor Desvenalfaxine Succinate Family 2 4
Danthron family 11 141
Noradrenergic re-uptake and Opioid receptor Ligand Tapentadol ... 21 79
Benzyl Alcohol family 1 73
NAD-dependent protein deacetylase sirtuin-1 Inhibitor SRT501 F... 19 88
Multidrug resistance protein Inhibitor Curcumin I Family 19 278
Arachidonate 5-lipoxygenase Inhibitor Caffeic Acid Family 3 32
Bile acid receptor Ligand SR-45023A (apomine) Family 3 34
Macrophage migration inhibitory factor and Prothrombin Inhibit... 2 49
Arachidonate 5-lipoxygenase and Prostaglandin G/H synthase 1 I... 2 19
Tyrosine-protein kinase Lck Inhibitor 2-(3,4,5-trihydroxy-benz... 2 6
Oestrogen receptor and Estrogen receptor beta Ligand 6-(4-hydr... 30 63
Arachidonate 15-lipoxygenase Inhibitor Hydrohalisulfate 1 Family 6 6
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 2 214
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand 4-(1,... 3 31
Thyroid hormone receptor alpha and Thyroid hormone receptor be... 5 8
Arachidonate 12-lipoxygenase, 12S-type and Arachidonate 15-lip... 3 7
Indoleamine 2,3-dioxygenase 1 Inhibitor Naphthalene-1,4-diol F... 2 4
Prostaglandin G/H synthase 1 Inhibitor 2-(2-methoxyphenyl)-1h-... 1 11
Tyrosinase Inhibitor 4-(6-hydroxynaphthalen-2-yl)benzene-1,3-d... 4 2
Tyrosinase Inhibitor 4-adamantyl Resorcinol Family 1 1
Estrogen receptor beta and Estrogen receptor ligand 3-fluoro-4... 6 42
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 2 14
Androgen receptor and Progesterone receptor ligand diarylpheno... 1 1
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 4 0
Arachidonate 5-lipoxygenase and Prostaglandin G/H synthase 1 i... 1 0
Lethal factor and Nuclear receptor ROR-gamma ligand CHEMBL1559... 1 2
Monoglyceride lipase inhibitor 7-(2-hydroxyphenyl)heptane-1-su... 1 2
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand 5-(2-... 3 0
Arachidonate 15-lipoxygenase and Nuclear receptor ROR-gamma li... 1 18
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand 1-[3,... 4 0
Carbonic anhydrase 12 and Carbonic anhydrase 9 inhibitor 2,2-d... 1 0
Arachidonate 5-lipoxygenase and Prostaglandin G/H synthase 1 i... 1 3
Eukaryotic elongation factor 2 kinase and Proto-oncogene tyros... 1 1
Retinoic acid receptor beta ligand Adarotene family 1 0
Arachidonate 5-lipoxygenase and Prostaglandin G/H synthase 1 i... 1 3
Prostaglandin G/H synthase 1 and Prostaglandin G/H synthase 2 ... 1 3
Acenes Metabolite 2-Methyl-1,4-naphthalenediol bis(dihydrogen ... 2 2
Phenols and Derivatives Metabolite 2-(Ethoxymethyl)phenol Family 1 14
2,4-diacetyl-5-hydroxy-3-(4-hydroxyphenyl)-5-methylcyclohexen-... 4 0
[(E)-3-carboxy-2-(5-methyl-2-oxidophenyl)prop-2-enyl]-(2-pheny... 3 0
Putative NP ZINC00526277 Family 2 2
2,4-bis(4-hydroxyphenyl)cyclobutane-1,3-dicarboxylate NP ZINC0... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00070089 DAP000662 Approved Drug Propofol
CFAMM00070139 DNAP001619 Approved Drug Thymol
CFAMM00070407 DNC009126 Investigative Drug 2,6-di-t-butylphenol
CFAMM00070008 DNC014753 Investigative Drug 4-Iodo-2,6-diisopropyl-phenol
CFAMM00070121 DNC001413 Investigative Drug TBHQ

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

21760 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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