CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name HBV polymerase inhibitor thymidine nucleoside analog Telbivudine Family
No. of Seeds 12 No. of Other Members 128
Family Centroid CFAMM00071212 Functional Category Approved Drug with Human Metabolite & Natural Product
Superfamily HBV, HIV polymerase, Thymidylate synthase inhibitor thymidine nucleoside analog Telbivudine Zidovudine Floxuridine Superfamily
Class Class 408

Cousin Family NamesSeedsMembers
HIV reverse transcriptase inhibitor thymidine nucleoside analo... 4 14
Thymidylate synthase inhibitor thymidine nucleoside analog Flo... 8 48
Reverse transcriptase Inhibitor Sorivudine Family 3 16
P2Y purinoceptor 2 Inhibitor Diquafosol Family 2 44
Uridine Triacetate family 2 8
DNA polymerase Inhibitor 5-propenyl-arabinofuranosyluracil 5'-... 1 1
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyroph... 3 24
Uridine 5'-monophosphate synthase Inhibitor 5-fluoro-6-iodo-um... 3 2
P2Y purinoceptor 6 inhibitor [[(2R,3S,4R,5R)-3,4-dihydroxy-5-(... 1 3
P2Y purinoceptor 14 and P2Y purinoceptor 6 inhibitor N,N-dieth... 3 17
Reverse transcriptase/RNaseH inhibitor 6-amino-3-[(3S,4S,5R)-5... 2 1
Reverse transcriptase/RNaseH inhibitor [[[difluoro(phosphono)m... 1 2
Reverse transcriptase/RNaseH inhibitor ddUTP family 1 0
P2Y purinoceptor 6 and P2Y purinoceptor 2 inhibitor [[[[(2R,3S... 1 0
Thymidine phosphorylase inhibitor [(2R,3aR,4R,6R,6aR)-6-(hydro... 1 1
Pyrimidine Nucleotides Metabolite Orotidylic acid Family 2 0


External ID

Functional Category

Molecule Name

CFAMM00071158 DNAP001483 Approved Drug Epervudine
CFAMM00071212 DAP000698 Approved Drug Telbivudine
CFAMM00071159 DNCL002601 Clinical Trial Drug 18F-fluorothymidine
CFAMM00071312 DCL001173 Clinical Trial Drug Clevudine
CFAMM00071191 DNC013529 Investigative Drug Edoxudine
CFAMM00071284 DNC013528 Investigative Drug 5-propyl-2'-deoxyuridine
CFAMM00071228 DNC000052 Investigative Drug 2'-deoxythymidine triphosphate
CFAMM00071233 DNC002925 Investigative Drug Thymidine-5'-Phosphate
CFAMM00071226 DNC000177 Investigative Drug Alovudine
CFAMM00071166 DNC000082 Investigative Drug 5'-deoxythymidine
CFAMM00071150 DNC002931 Investigative Drug Deoxythymidine
CFAMM00071293 DNC014838 Investigative Drug 3-(2-propyn-1-yl)thymidine

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

Last update by



55287 visits since 2014 .........


Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links


Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543