CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name HIV reverse transcriptase inhibitor thymidine nucleoside analog Zidovudine Family
No. of Seeds 4 No. of Other Members 14
Family Centroid CFAMM00071353 Functional Category Approved Drug with Natural Product
Superfamily HBV, HIV polymerase, Thymidylate synthase inhibitor thymidine nucleoside analog Telbivudine Zidovudine Floxuridine Superfamily
Class Class 408

Cousin Family NamesSeedsMembers
HBV polymerase inhibitor thymidine nucleoside analog Telbivudi... 12 128
Thymidylate synthase inhibitor thymidine nucleoside analog Flo... 8 48
Reverse transcriptase Inhibitor Sorivudine Family 3 16
Uridine Triacetate family 2 8
Reverse transcriptase/RNaseH inhibitor [[[difluoro(phosphono)m... 1 2
Reverse transcriptase/RNaseH inhibitor ddUTP family 1 0


External ID

Functional Category

Molecule Name

CFAMM00071353 DAP000701 Approved Drug Zidovudine
CFAMM00071365 DNC007832 Investigative Drug 5'-amino-5'-deoxy-alpha-D-thymidine
CFAMM00071350 DNC002928 Investigative Drug 3'-Azido-3'-Deoxythymidine-5'-Monophosphate
CFAMM00071363 DNC012846 Investigative Drug ZIDOVUDINE TRIPHOSPHATE

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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