CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFAD529
Family Name Prostaglandin G/H synthase 1 Inhibitor Mesalazine Family
No. of Seeds 2 No. of Other Members 30
Family Centroid CFAMM00072532 Functional Category Approved Drug with Human Metabolite & Natural Product
Superfamily Prostaglandin G/H synthase 1 Inhibitor Mesalazine Superfamily
Class Class 422

Cousin Family NamesSeedsMembers
Sodium channel protein type 10 subunit alpha Ligand Tetracaine... 6 166
Retinoic acid receptor alpha Ligand Tamibarotene Family 5 95
Cyclooxygenase Inhibitor Diclofenac Family 6 37
Prostaglandin G/H synthase 2 Inhibitor Mefenamic Acid Family 7 137
Serum albumin Inhibitor Iodipamide Family 2 23
M402 family 1 16
Beta-lactamase Inhibitor 4-[(methylsulfonyl)amino]benzoic Acid... 1 7
Neuraminidase Inhibitor 4-(acetylamino)-3-amino Benzoic Acid F... 2 27
Tyrosine-protein phosphatase non-receptor type 1 Ligand 2-(oxa... 3 11
Epidermal growth factor receptor and Tyrosine-protein kinase L... 1 26
Epidermal growth factor receptor Ligand 4-acrylamido-n-(3-brom... 2 20
3-oxo-5-alpha-steroid 4-dehydrogenase 2 Inhibitor 4-[4-(benzyl... 2 19
Carbonic anhydrase 2 Inhibitor 4-(4-tert-butylbenzylideneamino... 3 15
Acetylcholinesterase Inhibitor 3-(2,5-dioxo-pyrrolidin-1-yl)-b... 2 4
Glutamate receptor ionotropic, NMDA 2A and Glutamate receptor ... 3 8
Integrin beta-3 and Integrin alpha-V inhibitor SureCN7494201 f... 5 14
DNA-(apurinic or apyrimidinic site) lyase and ATP-dependent DN... 1 8
Dihydroorotate dehydrogenase (quinone), mitochondrial inhibito... 1 0
Aldo-keto reductase family 1 member C3 and Aldo-keto reductase... 1 0
Neprilysin inhibitor 5-[[(2S,4S)-2-benzyl-4-carboxy-5-phenylpe... 1 0
Nuclear receptor ROR-gamma and Lethal factor ligand NSC211094 ... 1 3
N-[3-[(E)-3-(dimethylamino)prop-2-enoyl]-4-hydroxyphenyl]aceta... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00072532 DAP000729 Approved Drug Mesalazine
CFAMM00072571 DNC002647 Investigative Drug Gabaculine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

48680 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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