CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFAD537
Family Name Prostaglandin G/H synthase 2 Inhibitor Celecoxib Family
No. of Seeds 3 No. of Other Members 97
Family Centroid CFAMM00073414 Functional Category Approved Drug with Human Metabolite
Superfamily Prostaglandin G/H synthase 2 Inhibitor Celecoxib Superfamily
Class Class 428

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 6 Ligand 4-(4,6-dinitro-1h-indol-... 4 19
Prostaglandin G/H synthase 2 Inhibitor SC-558 Family 1 2
Survival motor neuron protein and 15-hydroxyprostaglandin dehy... 1 35
5-hydroxytryptamine receptor 2A ligand SureCN5215979 family 2 10
Bifunctional epoxide hydrolase 2 and Prostaglandin G/H synthas... 7 20
Bifunctional epoxide hydrolase 2 and Prostaglandin G/H synthas... 2 0
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 1 1
Glucocorticoid receptor ligand 1-[(4aS)-6-(4-tert-butylphenyl)... 27 3
Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 ... 1 10
Carbonic anhydrase 2 and Carbonic anhydrase 1 inhibitor 4-(7-c... 1 1
Carbonic anhydrase 2 and Carbonic anhydrase 9 inhibitor 4-[4-(... 2 3
Carbonic anhydrase 9 and Carbonic anhydrase 2 inhibitor 3-[3-(... 2 0
Carbonic anhydrase 9 and Carbonic anhydrase 2 inhibitor 4-[5-(... 2 2
Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 ... 1 2
Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 ... 1 3
Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 ... 3 0
Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 ... 1 0
Prostaglandin G/H synthase 2 inhibitor SureCN8288067 family 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00073414 DAP000737 Approved Drug Celecoxib
CFAMM00073324 DNC004261 Investigative Drug SC-58125
CFAMM00073343 DNC013834 Investigative Drug Primary alcohol metabolite of celecoxib

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27255 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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