CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFAD541
Family Name Serotonin re-uptake inhibitor Dibenzazepine Clomipramine Family
No. of Seeds 2 No. of Other Members 23
Family Centroid CFAMM00073556 Functional Category Approved Drug
Superfamily Monoamine reuptake inhibitor Dibenzazepine Superfamily
Class Class 207

Cousin Family NamesSeedsMembers
Noradrenergic re-uptake inhibitor Dibenzazepine Imipramine Family 8 178
Nuclear receptor subfamily 1 group I member 3 ligand piperazin... 3 82
Potassium voltage-gated channel subfamily A member 3 Ligand CP... 4 26
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 9 67
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 5 47
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 3 34
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 5 18
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 6 45
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 53 289
D(4) dopamine receptor and Alpha-1B adrenergic receptor ligand... 1 2
D(4) dopamine receptor and Alpha-1B adrenergic receptor ligand... 7 27
D(4) dopamine receptor and Alpha-1B adrenergic receptor ligand... 2 6
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 3 0
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 3 0
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 4 3
Alpha-1D adrenergic receptor and Alpha-1B adrenergic receptor ... 1 0
D(4) dopamine receptor and 5-hydroxytryptamine receptor 2A lig... 1 4
Potassium voltage-gated channel subfamily H member 2 and D(3) ... 3 0
Potassium voltage-gated channel subfamily A member 3 ligand AG... 1 8
Sigma non-opioid intracellular receptor 1 and Sodium-dependent... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00073556 DAP000742 Approved Drug Clomipramine
CFAMM00073571 DNC000540 Investigative Drug Desmethylclomipramine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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